Social Services Grants for Nonprofits

National Institutes of Health · Amount varies

This NIH BRAIN Initiative R01 funds development of computational theories, models, and methods for analyzing complex brain-circuit data, to be shared with the research community. Eligible applicants are research organizations, including faith- or community-based organizations, tribal governments, foreign organizations, and U.S. territories; it targets institutions rather than individuals. No award amount is specified. The work is narrowly scoped to neural-circuit tool building, so confirm fit before applying.

National Institutes of Health · Up to $50K

The NIH parent Small Research Grant (R03, clinical trial not allowed) supports small, short-term projects such as pilot and feasibility studies, secondary data analysis, and methodology development. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget suits research institutions pursuing limited-scope projects to generate preliminary data.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial not allowed) supporting screening and functional validation of genomic variants linked to human congenital anomalies, developmental disabilities, and inborn errors of metabolism. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science genomics mechanism for research institutions.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial required) supports early-stage research projects with at least one clinical trial, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Up to $50K

An NIH/NICHD Small Research Grant (R03, clinical trial required) supporting small clinical-trial projects within the NICHD mission. Eligible applicants include a broad range of domestic and foreign institutions such as universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget and clinical-trial requirement make this best suited to research institutions running limited-scope pilot trials.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

This NIH program (Blueprint MedTech Translator) funds translational research and clinical feasibility studies for therapeutic and diagnostic devices targeting nervous- or neuromuscular-system disorders, open to a broad range of institutions including HBCUs, Hispanic-serving institutions, tribal colleges, faith- and community-based organizations, and individuals or businesses developing their own devices. It is a milestone-driven cooperative agreement requiring NIH staff involvement in project planning and monitoring. No award amount is specified, and the deadline is not imminent.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R21 funds projects that improve clinical-trial readiness for rare diseases — developing biomarkers and outcome measures, or characterizing a disease's course to enable future trials. Award size follows standard R21 limits.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.

National Institutes of Health · Up to $400K

This NIH R01 grant funds research into early immune system development from the prenatal period through early childhood, including effects of in-utero HIV or antiretroviral exposure. A broad range of applicants is eligible, including colleges and universities, tribal governments, faith- and community-based organizations, minority-serving institutions, and foreign organizations. The award ceiling is up to about $400,000.