National Institutes of Health Grants
598 open grant opportunities from National Institutes of Health, from Grants.gov — each with a plain-English summary of who qualifies, the deadline, and the award size.
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
Due in 2 daysNational Institutes of Health · $50K–$600K
This NIH (NCI) U24 cooperative agreement funds the continued operation and maintenance of established, widely-adopted informatics tools and resources used across cancer research; clinical trials are optional. Applicants must demonstrate that their resource is already widely used and has had significant impact, so it targets teams maintaining existing informatics infrastructure rather than new projects. Foreign organizations and the foreign components of U.S. organizations are eligible to apply, and foreign components are allowed. Awards range from about $50,000 to $600,000.
ResearchersSchools & universitiesLarge awardNarrow eligibilityLimited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
Due in 2 daysNational Institutes of Health · Up to $50K
This NIH R03 grant (up to $50,000) is a limited competition open only to current NCATS CTSA Program KL2 scholars and re-entry supplement recipients completing their transition to independent translational science careers. It's not open to researchers outside that specific CTSA cohort. The deadline is October 19, 2026.
ResearchersSmall awardNarrow eligibilityAdvanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
Due in 2 daysNational Institutes of Health · $50K–$600K
This NIH (NCI) U24 cooperative agreement funds advanced development and enhancement of emerging cancer informatics technologies that have passed initial prototyping but are not yet widely adopted; clinical trials are optional. It targets teams with a promising informatics tool ready for further development and broader impact, so eligibility is effectively oriented toward established research/informatics groups. Foreign organizations and the foreign components of U.S. organizations are eligible to apply, and foreign components are allowed. Awards range from about $50,000 to $600,000.
ResearchersSchools & universitiesLarge awardNarrow eligibilityCommunity Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)
Due in 2 daysNational Institutes of Health · Amount varies
This NIH U01 cooperative agreement funds a single Community Engagement Evaluation and Data coordination (CEED) hub to support a community-based participatory research consortium focused on oral health, coordinating data planning, community engagement evaluation, and operational support. Clinical trials are not allowed, and as a cooperative agreement NIH staff are substantially involved. This is a narrow, single-hub coordination role rather than a broad research grant. Foreign organizations, the foreign components of U.S. organizations, and foreign components are not eligible or allowed; see the NOFO for full eligibility details. No award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityOptimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
Due in 5 daysNational Institutes of Health · Amount varies
This NIH/NIMH R34 grant supports pilot research to adapt, optimize, and test behavioral interventions for sleep problems in adolescents and young adults with or at risk for a mental health disorder, and a clinical trial is required. It is a research grant for universities, research institutions, and similar eligible organizations. Foreign (non-U.S.) organizations and foreign components are not eligible. No specific award amounts are listed, and eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesGREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
Due in 13 daysNational Institutes of Health · Up to $1.3M
This NIH U01 grant establishes the GREGoRi Data Coordination and Outreach Center, which coordinates the rare disease research program and makes its protocols, data, tools, and resources available to the broader community; clinical trials are not allowed. It is a research grant for universities, research institutions, and similar eligible organizations. Foreign organizations and foreign components are not eligible to apply. The award maximum is about $1.25 million. Eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesLarge awardGREGoRi Technology Integration Center (U01, Clinical Trials Optional)
Due in 13 daysNational Institutes of Health · Up to $2.3M
This NIH U01 grant establishes the GREGoRi Technology Integration Center to set standards and best practices for applying new molecular methods in rare disease diagnosis, including building a benchmarking dataset; clinical trials are optional. It is a research grant for universities, research institutions, and similar eligible organizations. Foreign organizations and foreign components are not eligible to apply. The award maximum is about $2.25 million. Eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesLarge awardPopulation Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)
Due in 13 daysNational Institutes of Health · Amount varies
This NIH X01 opportunity provides access to biospecimens (urine, plasma, serum, genomic DNA) and related data from the Population Assessment of Tobacco and Health (PATH) Study rather than direct research funding. It is aimed at investigators at universities, research institutions, and similar eligible organizations, including various minority-serving institutions and tribal entities. Foreign (non-U.S.) organizations and foreign components are not eligible. No award amounts are listed; this is a resource-access mechanism for researchers, not a general grant for nonprofits, businesses, or individuals.
ResearchersSchools & universitiesGovernment / tribalGREGoRi Innovation Projects (U01 Clinical Trial Optional)
Due in 13 daysNational Institutes of Health · $3–$500K
This NIH U01 grant funds development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, with clinical trials optional. It is a research grant for universities, research institutions, and similar eligible organizations, and foreign organizations and foreign components are eligible. The award maximum is about $500,000 (the listed minimum appears to be a data artifact). Eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesLarge awardExploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
Due in 16 daysNational Institutes of Health · Amount varies
This NIH R61 grant supports exploratory clinical trials in arthritis, musculoskeletal, and skin diseases, and a clinical trial is required. It is a research grant for universities, research institutions, and similar eligible organizations, including various minority-serving institutions and tribal entities. Foreign (non-U.S.) organizations are not eligible to apply, though defined foreign components are allowed. No specific award amounts are listed, and eligibility is oriented toward research institutions rather than nonprofits, small businesses, or individuals broadly.
ResearchersSchools & universitiesGovernment / tribalClinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
Due in 16 daysNational Institutes of Health · Amount varies
This NIH R01 grant funds clinical observational studies in musculoskeletal, rheumatic, and skin diseases. It is a research grant for universities, research institutions, and similar eligible organizations, including various minority-serving institutions and tribal entities. Foreign (non-U.S.) organizations are not eligible to apply, though defined foreign components are allowed; clinical trials are not permitted under this opportunity. No specific award amounts are listed, and eligibility is oriented toward research institutions rather than nonprofits, small businesses, or individuals broadly.
ResearchersSchools & universitiesGovernment / tribalDeveloping novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
Due in 19 daysNational Institutes of Health · Amount varies
This NIH R01 grant supports development of novel theory and methods to understand how genetic and non-genetic factors shape complex human traits, using interdisciplinary modeling and large-scale datasets. It is a research grant aimed primarily at universities, research institutions, and similar eligible organizations, including various minority-serving institutions, tribal entities, and foreign organizations. No award amounts are specified. Clinical trials are not allowed under this opportunity, and the eligibility list is research-institution oriented rather than open to nonprofits, small businesses, or individuals broadly.
ResearchersSchools & universitiesGovernment / tribalSecondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Due in 20 daysNational Institutes of Health · Up to $350K
This NIH/NCI R01 grant funds secondary analysis and integration of existing datasets to study cancer risk and related outcomes such as survival and treatment response. It is a research grant for universities, research institutions, and similar eligible organizations, including various minority-serving institutions, tribal entities, and foreign organizations. The award maximum is about $350,000. Eligibility is oriented toward research institutions rather than nonprofits, small businesses, or individuals broadly, and applicants typically need access to relevant existing data.
ResearchersSchools & universitiesGovernment / tribalEarly-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
Due in 24 daysNational Institutes of Health · Up to $150K
This NIH/NCI R61 grant funds early-stage, proof-of-concept development of innovative technologies for molecular or cellular characterization of cancer and biospecimen handling; clinical trials are not allowed. It is a research grant for universities, research institutions, and similar eligible organizations, and foreign organizations and foreign components are eligible. The award maximum is about $150,000. Eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesAmyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
Due in 24 daysNational Institutes of Health · Amount varies
This NIH U01 grant funds research using expanded-access data for investigational drugs to help intermediate-size populations of ALS patients who are not eligible for ongoing clinical trials; a clinical trial is required. Eligibility is narrow: applicants must be clinical trial sites participating in a phase 2/3 or phase 3 trial sponsored by a small business that is the FDA-designated sponsor of the relevant drug. Foreign organizations and foreign components are not eligible. No award amounts are listed. This is a highly specialized opportunity tied to an existing small-business-sponsored ALS drug trial, not a general grant.
ResearchersSmall businessNarrow eligibilityAdvanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
Due in 24 daysNational Institutes of Health · Up to $300K
This NIH/NCI R33 grant funds advanced development and technical validation of emerging technologies for molecular or cellular characterization of cancer and biospecimen handling, where feasibility has been shown but further validation is needed; clinical trials are not allowed. It is a research grant for universities, research institutions, and similar eligible organizations, and foreign organizations and foreign components are eligible. The award maximum is about $300,000. Eligibility is oriented toward research institutions rather than nonprofits, businesses, or individuals broadly.
ResearchersSchools & universitiesNCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Due in 27 daysNational Institutes of Health · Up to $1.1M
NIH (NCCIH) R33 funding for early-phase clinical trials of natural products (botanicals, dietary supplements, probiotics) to confirm target engagement and inform whether further clinical research is warranted. Intended for research institutions; foreign organizations are not eligible. The listed maximum is about $1,050,000. It will not support efficacy or effectiveness trials and requires strong preliminary data, making it narrow research-only funding.
ResearchersSchools & universitiesLarge awardNarrow eligibilityNIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
Due in 27 daysNational Institutes of Health · Up to $750K
NIH (NIDA) K12 institutional career-development funding to support mentored research training for clinician-scientists in substance use and substance use disorder research. Intended for institutions that will run a scholar training program; foreign organizations are not eligible and foreign components are not allowed. The listed maximum is about $750,000. This is an institutional training award, not a grant for individuals or general nonprofits.
Schools & universitiesResearchersLarge awardNarrow eligibilityNCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
Due in 27 daysNational Institutes of Health · Amount varies
NIH (NCCIH) R01 funding for mid-phase clinical trials of natural products such as botanicals, dietary supplements, and probiotics that already have strong preliminary data. Intended for research institutions able to conduct hypothesis-driven, milestone-based clinical trials; foreign organizations are not eligible. No dollar amount is stated. It will not support efficacy/effectiveness trials or cancer-treatment trials, and requires substantial prior preliminary data, so it is narrow in scope.
ResearchersSchools & universitiesNarrow eligibilityNCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Due in 27 daysNational Institutes of Health · Up to $350K
NIH (NCCIH) phased R61/R33 funding for early-phase clinical trials of natural products (botanicals, probiotics, marketed dietary supplements) with a strong scientific rationale. Suited to research institutions running milestone-driven pharmacokinetic and target-engagement studies; foreign organizations are not eligible. The listed maximum is about $350,000. It is narrow research-only work requiring strong preliminary justification, not a fit for individuals or general nonprofits.
ResearchersSchools & universitiesNarrow eligibility
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How many National Institutes of Health grants are open right now?
UseGrants is tracking 598 open National Institutes of Health opportunities. The next one closes Oct 19, 2026. The largest published award ceiling on this page is $2,250,000. The list is rebuilt from public records daily, so an opportunity drops off it the day its deadline passes.
Who can apply for National Institutes of Health funding?
Eligibility is set per opportunity, not per agency — the same funder will run one program open to any nonprofit and another restricted to accredited universities. Across the National Institutes of Health opportunities listed here the recurring eligibility signals are researchers, schools & universities, large award and narrow eligibility. Every listing still states its own terms in plain English; confirm them on the funder's official notice before you apply.