Browse grants
Federal opportunities with plain-English eligibility summaries. We aggregate public records — always verify the details on the funder’s site before applying.
Biomechanics and Mechanobiology
No deadline listedU.S. National Science Foundation · $5K–$400K
The Biomechanics and Mechanobiology (BMMB) program is part of the Mechanics of Materials cluster within the Division of Civil, Mechanical, and Manufacturing Innovation. The BMMB program supports fundamental and transformative research that advances our understanding of engineering biomechanics and/or mechanobiology. The program emphasizes the study of biological mechanics across multiple domains, from sub-cellular to whole organism. Distinct from conventional engineering materials, the program encourages the consideration of diverse living tissues as smart materials that are self-designing. BMMB projects must have a clear biological component, a clear mechanics component, and must improve our understanding of the mechanical behavior of a living system. Investigations of the mechanical behavior of biological molecules, cells, tissues, and living systems are welcome. An important concern is the influence of in vivo mechanical forces on cell and matrix biology in the histomorphogenesis, maintenance, regeneration, repair, and aging of tissues and organs. The program is also interested in efforts to translate recent biomechanical and mechanobiological discoveries into engineering science. Multiscale mechanics approaches are encouraged but not required. Projects may include theoretical, computational, or experimental approaches, or a combination thereof. NSF does not support clinical trials; however, feasibility studies involving human volunteers or animal subjects may be supported if appropriate to the scientific objectives of the project. Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is essential to address why the proposed work is important in terms of engineering science, and to state the potential impact of success in the research on society and/or industry. Innovative proposals outside of these specific areas of biomechanics and mechanobiology will be considered. However, prior to submission of particularly unique topics, it is strongly recommended that Principal Investigators (PIs) contact the program director to discuss how the proposed work fits within the scope of the program and avoid the possibility of the proposal being returned without review. Related programs also fund certain aspects of biomechanics and mechanobiology research, and PIs are encouraged to examine these to find the appropriate program for submission. Proposals with a heavy emphasis on tissue engineering or developing validated models of tissue and organ systems should consider the Engineering of Biomedical Systems (EBMS) program.Projects addressing biological questions about the physiological mechanisms and structural features of organisms should consult the Physiological Mechanisms & Biomechanics (PMB) program.Projects elucidating aspects of neural control may consider the Perception, Action, & Cognition (PAC) program or the Mind, Machine, and Motor Nexus (M3X) program if the project contains work relevant to human-machine interaction. Projects in rehabilitation engineering should consider the Disability and Rehabilitation Engineering (DARE) program. Projects focused on fundamental research related to design, characterization, and modification of biomaterials should consider the Biomaterials (BMAT) program. Manufacturing systems proposals should consider the Advanced Manufacturing (AM) program. Work on the interplay between structure, dynamics, and function of biomolecules without advancing our understanding of the mechanics of a living system should consider the Molecular Biophysics program. Researchers who believe their work may span multiple programs are particularly encouraged to contact the cognizant program directors well in advance of submission. The duration of unsolicited proposal awards is generally up to three years; proposals for a shorter duration are welcome. Single-investigator award budgets typically include support for one graduate student (or equivalent trainee) and up to one month of PI time per year (awards for multiple investigator projects are typically larger). Proposal budgets or durations that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.
Engineering Design and Systems Engineering
No deadline listedU.S. National Science Foundation · Amount varies
The Engineering Design and Systems Engineering (EDSE) program supports fundamental research that advances design science and/or systems science through the creation of new knowledge about the design of engineered artifacts. Engineered artifacts include, but are not limited to, devices, products, processes, platforms, materials, organizations, systems, and systems of systems. The program focuses on design as a system, in which designers, the artifacts they create, the methods they use to create them, and the environment in which this occurs are all subject to rigorous scientific inquiry, along with the interactions among these elements. The EDSE program strongly encourages proposals that embrace the multidisciplinary nature of design and supports well-defined collaborations of experts in design science and/or systems science with experts in other domains, including (but not limited to) the social, behavioral, computational, and natural (biological and physical) sciences. Competitive proposals will be firmly grounded in theory, will demonstrate the potential of the proposed work to improve design, and will include a plan to rigorously assess the performance and effectiveness of the proposed research methods across all domains involved. In particular, the EDSE program supports fundamental contributions in areas that include but are not limited to design representation; design optimization; design validation; mechanism design; robotics and intelligent system design; design of engineered materials systems; design cognition; design collaboration; data science and artificial intelligence in design; design in under-resourced communities; immersive design; and design at extreme scales and in extreme environments. Prospective investigators are encouraged to discuss their research ideas with the Program Director in advance of proposal preparation and submission.
Mechanics of Materials and Structures
No deadline listedU.S. National Science Foundation · Amount varies
The Mechanics of Materials and Structures program supports fundamental research in mechanics as related to the behavior of deformable solid materials and structures under internal and external actions. The program supports a diverse spectrum of research with emphasis on transformative advances in experimental, theoretical, and computational methods. Submitted proposals should clearly emphasize the contributions to the field of mechanics. Proposals related to material response are welcome, including, but not limited to, advances in fundamental understanding of deformation, fracture, and fatigue as well as contact and friction. Proposals that relate to structural response are also welcome, including, but not limited to, advances in the understanding of nonlinear deformation, instability and collapse, and wave propagation. Proposals addressing mechanics at the intersection of materials and structures, such as, but not limited to, meta-materials, hierarchical, micro-architectured and low-dimensional materials are also encouraged. Proposals that explore and build upon advanced computing techniques and tools to enable major advances in mechanics are particularly welcome. For example, proposals incorporating reduced-order modeling, data-driven techniques, and/or stochastic methods with a strong emphasis on validation are encouraged. Also welcome are proposals addressing data analytics for deformation or damage response deduction from large experimental and computational data sets. Similarly, proposals that explore new experimental techniques to capture deformation and failure information for extreme ranges of loading or material behavior are also encouraged. Finally, experimental and computational methods that address information across multiple length and time scales, potentially involving multiphysics considerations are also welcome. Proposals with a focus on buildings and civil infrastructure system are welcome in CMMI and should be submitted to the program on Structural and Architectural Engineering Materials (SAEM). Proposals addressing processing and mechanical performance enhancements should be submitted to the Materials Engineering and Processing (MEP) program. Investigators with proposals focused on design methodological approaches and theory enabling the accelerated development and insertion of materials should consider the Design of Engineering Material Systems (DEMS) program. Lastly, investigators with interest in developing a combined theoretical and experimental approach to accelerate materials discovery and development should direct their proposals to the Designing Materials to Revolutionize and Engineer Our Future (DMREF) opportunity. Proposers are actively encouraged to email a one-page project summary to MOMS@nsf.gov before full proposal submission to determine if the research topic falls within the scope of the MOMS program.
Engineering for Civil Infrastructure
No deadline listedU.S. National Science Foundation · Amount varies
The Engineering for Civil Infrastructure (ECI) program supports fundamental research in geotechnical, structural, materials, architectural, and coastal engineering. The ECI program promotes research that can shape the future of the nation’s physical civil infrastructure and that can contribute to climate change adaptation and mitigation, and hazards and disaster resilience. Types of civil infrastructure that the ECI program considers include, but are not limited to, buildings, residential construction, earth and earth retaining structures, and components of flood protection systems; water, waste disposal, and wastewater systems; energy infrastructure (excluding nuclear); and transportation systems (excluding pavements). Both disciplinary and convergent research that can address the challenges of physical civil infrastructure to be resilient and sustainable over its service lifetime are of particular interest. Broader impacts of ECI research include fostering community welfare for an equitable and prosperous nation and promoting environmentally friendly, circular economy policies. The ECI program supports research that advances knowledge on the behavior of physical civil infrastructure subjected to and interacting with the natural environment during construction; under service and long-term conditions, including increased demands due to climate change adaptation and other emerging stressors; and under conditions caused by single or multiple extreme hazard events (extreme weather, windstorms, earthquakes, tsunamis, storm surges, landslides, and fire, including wildland-urban interface fire). The ECI program also supports research on geomaterials and infrastructure materials utilized in load-bearing systems as well as in non-structural systems. Of particular interest is experimental and analytical/computational research to advance the fundamental understanding of coupled multi-physics, multi-scale (spatial and temporal), multi-functional behavior of these materials and their intended use in civil infrastructure. The ECI program supports research on civil infrastructure that contributes to the National Science Foundation’s role in the National Earthquake Hazards Reduction Program (NEHRP) and the National Windstorm Impact Reduction Program (NWIRP). Principal Investigators are encouraged to leverage NSF’s investments in the Natural Hazards Engineering Research Infrastructure (NHERI) experimental, computational modeling and simulation, and data resources ( https://www.designsafe-ci.org/ ) in their research to accelerate advances needed for reducing the impacts of natural hazards on civil infrastructure. The NHERI Science Plan ( https://www.designsafe-ci.org/facilities/nco/science-plan/ ) offers a range of research topics that could benefit from the use of NHERI resources and are relevant to the ECI program. The ECI program does not support research that addresses natural resource exploration or recovery, investigates blasts and explosions, develops sensor and measurement technologies, or focuses on hazard characterization. The ECI program only supports fundamental research topics for civil infrastructure with a strong grounding in theory. Topics which fall within the mission for research and/or development of other federal and state agencies are appropriate for the ECI program only when addressing fundamental scientific questions. Research on natural hazard characterization is supported through programs in the NSF Directorate for Geosciences. Proposers are actively encouraged to email a one-page project summary to the ECI Program Officers before submitting a full proposal for guidance on whether the proposed research topic falls within the scope of the ECI program; this guidance especially should be requested for multi-disciplinary research proposals, proposals for which research and/or development on the subject civil infrastructure(s) are also supported by other federal and state agencies, and proposals that consider civil infrastructure not listed above.
Operations Engineering
No deadline listedU.S. National Science Foundation · Amount varies
The Operations Engineering (OE) program supports fundamental research on advanced analytical methods for improving operations in complex decision-driven environments. Analytical methods include, but are not limited to, deterministic and stochastic modeling, optimization, decision and risk analysis, data science, and simulation. Methodological research is highly encouraged but must be motivated by problems that have potential for high impact in engineering applications. Application domains of particular interest to the program arise in commercial enterprises (e.g., production/manufacturing systems and distribution of goods, delivery of services), the public sector/government (e.g., public safety and security), and public/private partnerships (e.g., health care, environment and energy). The program also welcomes operations research in new and emerging domains and addressing systemic societal or technological problems. The OE program particularly values cross-disciplinary proposals that leverage application-specific expertise with strong quantitative analysis in a decision-making context. Proposals for methodological research that are not strongly motivated by high-potential engineering applications are not appropriate for this program. PIs are encouraged to send any program inquiries to both Program Directors.
National Facilities
No deadline listedU.S. National Science Foundation · Amount varies
The National Facilities program supports the operation of national user facilities: National Facilities areresearch facilities with specialized instrumentation available to the scientific research community in general and the materials research community in particular.These facilities provide unique research capabilities that can be located at only a few highly specialized laboratories in the Nation. They provide open user service for scientists and engineers from a broad range of disciplines including biology, chemistry, geosciences, materials research. and physics. Theyinclude facilities and resources for research using high magnetic fields, ultraviolet and x-ray synchrotron radiation, neutron scattering, and nanofabrication. Theyserve as science and technology-related resources and experiences for students. Theyconduct student and teacher education, general public awareness activities, curriculum development, and educational research.
R Package Development and Data Certification for the National Park Service Units of the National Capital Region and the Northeast
No deadline listedNational Park Service · $1–$90K
The objective of this Agreement is to advance historic preservation at the local level by establishing a task agreement between the National Park Service and the National Alliance of Preservation Commissions (NAPC) to provide training opportunities, promote the Federal Certified Local Government program, and strengthen local preservation commissions by providing bi-annual State Certified Local Government Coordinator Training
Fluid Dynamics
No deadline listedU.S. National Science Foundation · Amount varies
TheFluid Dynamicsprogram is part of the Transport Phenomena cluster, which also includes 1) theCombustion and Fire Systemsprogram; 2) theParticulate and Multiphase Processesprogram; and 3) theThermal Transport Processesprogram. TheFluid Dynamicsprogram supports fundamental research toward gaining an understanding of the physics of various fluid dynamics phenomena. Proposed research should contribute to basic scientific understanding via experiments, theoretical developments, and computational discovery. Major areas of interest and activity in the program include: Turbulence and transition: High Reynolds number experiments; large eddy simulation; direct numerical simulation; transition to turbulence; 3-D boundary layers; separated flows; multi-phase turbulent flows; flow control and drag reduction. High-speed boundary layer transition and turbulence at Mach numbers greater than 5 to understand modal and/or non-modal interactions leading to boundary layer transition and the ensuing developing and fully developed turbulent boundary layer flows.Combined experiments and simulations are encouraged. Bio-fluid physics:Bio-inspired flows; biological flows with emphasis on flow physics. Non-Newtonian fluid mechanics:Single-phase viscoelastic flows; solutions of macro-molecules. Bubble dynamics: Bubbles related to cavitation and/or drag reduction or impacting the fluid viscosity (locally) or manipulation of bubbles with external excitation (acoustofluidics). Microfluidics and nanofluidics: Micro-and nano-scale flow physics. Wind and ocean energy harvesting: Focused on fundamental fluid dynamics associated with renewable energy. The NSF-DOE (Department of Energy) joint funding area is focused on high Reynolds number aerodynamics of thick airfoils (> 21% thickness/chord) operating in complex (3D) steady, unsteady, and separated flows. Impacts of blade surface quality/roughness rotor performance on the aerodynamic/aeroelastic performance of novel rotor geometries and supporting structures are also of interest. Air/sea interactions, including waves/currents, on the hydrodynamic loading for offshore wind turbines. Improved measurement techniques and sensing/control technologies required to characterize the metocean environment impact on performance. The DoE participates in this initiative throughthe Wind Energy Technologies Office (program manager Michael Derby, email: michael.derby@ee.doe.gov). Fluid-structure interactions:General FSI applications across the low- to high-Reynolds number range are of interest to NSF. In addition, NSF-AFOSR (Air Force Office of Scientific Research) joint funding area is focused on theory, modeling and/or experiments for hypersonic applications. AFOSR participates in this initiative through the Aerothermodynamics program. Canonicalconfigurations:Experimental research is encouraged to develop spatiotemporally resolveddatabases for canonical configurations to either confirm historicalresults or to provide data in an unexplored parameter region. Fidelity and completeness for theoretical/computational validation is a key attribute of theproposed experimental data. Artificial intelligence (AI)/machine learning:Innovative AI ideas related to the use of machine learning and other AI approaches in fluid dynamics research to model and control the flows are encouraged.Verifying new models with canonicalconfigurations, when appropriate, is encouraged for theComputational andData-Enabled Science & Engineering(CDS&E) program. Instrumentation and Flow Diagnostics: Instrument development for time-space resolvedmeasurements; shear stress sensors; novel flow imaging; and velocimetry. NOTE:Proposals that use fluid flows as a boundary input condition or a driving force in a problem do not fit within the scope of this program. Proposals focused on particulates (including droplets) two-way coupled with fluids, colloids, and multiphase rheology and processes should be directed to the Particulate andMultiphase Processesprogram. Proposals dealing mainly with materials synthesis, processing and characterization may be more suitable for theAdvanced Manufacturingprogramin the Division of Civil, Mechanical, and Manufacturing Innovation orprograms in theDivision of Materials Research. Proposals dealing primarily with sensors and controls may be more suitable for the Dynamics, Controls, & Cognition program in the Division of Civil, Mechanical, and Manufacturing Innovation. Proposals focused on biological systems may be more suitable forPhysiological and Structural Systemsin the Division of Integrative Organismal Systems. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field.Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the "What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)" link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged.Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate.Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide (PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposalsthat are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.
Process Systems, Reaction Engineering, and Molecular Thermodynamics
No deadline listedU.S. National Science Foundation · Amount varies
TheProcess Systems, Reaction Engineering, and Molecular Thermodynamicsprogram is part of the Chemical Process Systems cluster, which also includes: 1) theCatalysisprogram; 2) theElectrochemical Systemsprogram; and 3) theInterfacial Engineeringprogram. The goal of theProcess Systems, Reaction Engineering, and Molecular Thermodynamicsprogram is to advance fundamental engineering research on the rates and mechanisms of chemical reactions, systems engineering, and molecular thermodynamics as they relate to the design and optimization of chemical reactors and the production of specialized materials that have important impacts on society. The program supports the development of advanced optimization and control algorithms for chemical processes, molecular and multi-scale modeling of complex chemical systems, fundamental studies on molecular thermodynamics, and the integration of these methods and concepts into the design of novel chemical products and manufacturing processes. This program supports sustainable chemical manufacturing research on the development of energy-efficientchemical processes and environmentally-friendly chemical products through concurrent chemical product/process design methods.Sustainability is also enhanced by research that promotes the electrification of the chemical process industries over current thermally-activated processes. Proposals should focus on: Chemical reaction engineering: This area encompasses the interaction of transport phenomena and kinetics in reactive systems and the use of this knowledge in the design of chemical reactors.Research areas include(1) development of novel reactor designs, such as catalytic and membrane reactors, micro-reactors, chemical vapor and atomic layer deposition systems, (2) studies of reactions in supercritical fluids, (3) novel reaction activation techniques such as atmospheric pressure plasmas (which may be submitted under the ECLIPSE meta-program) and microwave radiation, (4) design of multifunctional and intensified systems, such as chemical-factory/lab-on-a-chip concepts, (5) nanoparticle nucleation, growth, and surface functionalization, and (6) biomass conversion to fuels and chemicals.The program also supports new approaches that enable the design of modular chemical manufacturing systems such as distributed hydrogen and ammonia production processes. Process design, optimization, and control: This area encompasses process systems science, including the development of process modeling, design, control and optimization theory and algorithms; process development proposals are not appropriate for this program.High-priority research topics include process intensification, modular process systems, smart manufacturing, large-scale carbon dioxide capture and conversion, computational tools (including those based on quantum computing methods) enabling advanced chemical manufacturing, real-time optimization and control of large-scale chemical systems with quantitative sustainability metrics, machine learning, and optimization of enterprise-wide processes involving planning, scheduling, and real-time control to create resilient supply chains. Reactive polymer processing: Program scope in this area is limited to research that integrates synthesis and processing to engineer specific nanoscale structures and compositions to tune the macroscopic scale properties of polymers, such as their ability to biodegrade or to be recycled. The focus is on reactive processes that address these environmental concerns while producing tailor-made macromolecular materials. Molecular thermodynamics: This area focuses on fundamental research that combines principles of classical thermodynamics, statistical mechanics, and atomistic-scale simulations to improve chemical processing and to facilitate synthesis of novel functional materials such as catalysts, polymers, solvents, and colloids. Topics include fundamental studies on self- and directed-assembly of nanoscale-level patterned polymer films, machine-learning methods to predict structure-property relationships, large-ensemble molecular dynamics simulations, simulation of peptide self-assembly and protein interactions, and behavior of multiphase and reactive systems under nanoscale confinement. The ultimate goal of research supported by this program is to enable the development of more efficient chemical processes, improve environmental sustainability and water quality, and design functional materials with tailored properties. Innovative proposals outside of these specific interest areas may be considered.However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review. Hypothesis-driven research plans are encouraged. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of principal investigator time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the Program Director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the Program Director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in theProposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals. COMPLIANCE: Proposals which are not compliant with the Proposal and Award Policies and Procedures Guide (PAPPG) will be returned without review.
Disability and Rehabilitation Engineering
No deadline listedU.S. National Science Foundation · Amount varies
The Disability and Rehabilitation Engineering program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Engineering of Biomedical Systems program. The Disability and Rehabilitation Engineering program supports fundamental engineering research that will improve the quality of life of persons with disabilities through the development of new theories, methodologies, technologies, or devices. Disabilities could be developmental, cognitive, hearing, mobility, visual, selfcare, independent living, or other. Proposed projects must advance knowledge regarding a specific human disability or pathological motion or understanding of injury mechanisms. Research may be supported that is directed toward the characterization, restoration, rehabilitation, and/or substitution of human functional ability or cognition, or to the interaction between persons with disabilities and their environment. Areas of particular interest are neuroengineering, rehabilitation robotics, brain-inspired assistive or rehabilitative systems, theoretical or computational methods, and novel models of functional recovery including the development and application of artificial physiological systems. Emphasis is placed on significant advancement of fundamental engineering knowledge that facilitates transformative outcomes. The DARE Program encourages high-risk/high-reward proposals that surpass incremental technological improvements. The DARE Program also encourages participatory design and the inclusion of trainees with disabilities as part of the proposed research or broader impacts. Innovative proposals outside of the above specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the Program Director to avoid the possibility of the proposal being returned without review. NSF does not support clinical trials; however, feasibility studies involving human volunteers may be supported if appropriate to the project objectives. The development and application of artificial physiological systems that do not model functional recovery and instead improve fundamental understanding of physiological and pathophysiological processes would be appropriate for EBMS. Furthermore, the DARE program does not support proposals having as their central theme commercialization of a product. Small businesses seeking early stage R&D funding for product development are encouraged to contact the NSF SBIR/STTR program in the America's Seed Fund within the Directorate for Technology, Innovation and Partnerships (TIP). INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact of success in the research on society and/or industry. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of principal investigator time per year (awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the Program Director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the "What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)" link towards the bottom of this page. Faculty Early Career Development (CAREER) program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants for Facilitation Awards For Scientists And Engineers With Disabilities (FASED), EArly-concept Grants for Exploratory Research (EAGER), and Rapid Response Research (RAPID) are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI) proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that FASED, EAGER, RAPID, and GOALI proposals can be submitted anytime during the year. Details about FASED, EAGER, RAPID, and GOALI are available in the Proposal & Award Policies & Procedures Guide (PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposals that are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.
Cellular and Biochemical Engineering
No deadline listedU.S. National Science Foundation · Amount varies
Synopsis TheCellular and Biochemical Engineering(CBE)program is part of theEngineering Biology and Healthcluster, which also includes: 1) theBiophotonicsprogram; 2) theBiosensingprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram. TheCellular and Biochemical Engineeringprogram supports fundamental engineering research that advances understanding of cellular andbiomolecular processes. CBE-funded research may lead to the development of enabling technology for advanced biomanufacturing of therapeutic cells, biochemicals, and biopharmaceuticals, and for otherbiotechnology industrie. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches. Fundamental to many CBE research projects is the understanding of how biomolecules, subcellular systems, cells, and cell populations interact, and how those interactions lead to changes in structure, function, and behavior. A quantitative treatment of problems related to biological processes is considered vital to successful research projects in the CBE program. Major areas of interest for the program include: Metabolic engineering and synthetic biology for biomanufacturing, The design of synthetic metabolic components and synthetic cells, Microbiome structure, function, maintenance, and design, Protein and enzyme engineering, and Design of integrated chemoenzymatic systems. The CBE program also encourages proposals that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities. All proposals should include a description on the potential impact of proposed research on an associated biomanufacturing process. Proposals whose core innovation involves tissue engineering, organ culture, development of models of healthy or diseased physiology, or design and application of technologies focused on the diagnosis or treatment of disease should be submitted to theEngineering ofBiomedicalSystemsprogram(CBET 5345). Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact of success in the research on society and/or industry. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of principal investigator time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the Program Director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page. Faculty Early Career Development(CAREER) program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements : Principal Investigators are strongly encouraged to discuss their requests with the Program Director before submission of the proposal. Grants forRapid Response Research(RAPID) and EArly-concept Grants for Exploratory Research(EAGER) are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI) proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance : Proposals that are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.
Space Technology Research, Development, Demonstration, and Infusion (SpaceTech REDDI-2026)
No deadline listedNASA Headquarters · Amount varies
The National Aeronautics and Space Administration (NASA) Headquarters, Space Technology Mission Directorate (STMD) will be releasing an Umbrella NASA Research Announcement (NRA) titled “Space Technology Research, Development, Demonstration, and Infusion-2026 (SpaceTech-REDDI-2026)” on or about December 9, 2025. The solicitation is available by opening the NSPIRES homepage at https://nspires.nasaprs.com/ , selecting “Open” under "Solicitations," and searching "Space Technology Research, Development, Demonstration, and Infusion-2026 (SpaceTech-REDDI-2026)" un- der Solicitation #/Keyword(s). Proposals will be solicited through Appendices issued under this Umbrella SpaceTech-REDDI-2026 Solicitation, as technology topics are defined and funding is made available. See STMD Solicitations and Opportunities ( https://www.nasa.gov/stmd-solicitations-and-opportunities/ ) for anticipated releases. Once new Appendices are released, interested parties will be able to access the Appendices by selecting “Open” under "Solicitations," and searching “SpaceTech- REDDI-2026” in the “Solicitation #/ Keyword(s)” search area, and then selecting “List of Open Program Elements”. It is anticipated that this Umbrella NRA Solicitation (SpaceTech-REDDI-2026) will be open for one year and Umbrella SpaceTech-REDDI Solicitations will be issued annually. NASA STMD leads the development, demonstration, and infusion of transformational space technologies that solve critical stakeholder needs. As the tech base for civil space, STMD advances technology to sup- port future NASA, other government, and commercial missions. STMD investments aim to (1) advance U.S. space technology innovation and competitiveness in a global context, (2) encourage technology driven economic growth with an emphasis on the expanding space economy, and (3) inspire and develop a powerful U.S. aerospace technology community. STMD bolsters and funds ideas from entrepreneurs, researchers, and innovators across the country. Space technology research and development occurs at NASA centers, universi- ties, national labs, and small businesses. Interested proposers should monitor the NSPIRES website. NASA Headquarters maintains an electronic notification system to alert interested parties of program announcements, including solicitations and associated amendments. Subscription to this service is free to all registered users of NSPIRES at https://nspires.nasaprs.com . To add or change a subscription to the electronic notification system for a specific pro- gram or a NASA Mission Directorate, users should login to the database system and select “Account Management,” then “Email Subscriptions.” It is the responsibility of the prospective proposer to check this solicitation’s NSPIRES page for updates. Further questions concerning the Space Tech-REDDI-2026 solicitation may be sub- mitted to: HQ-STMD-SpaceTech-REDDI@nasaprs.com . Responses to inquiries will be answered by e-mail and may also be included in the Frequently Asked Questions (FAQ) document located on the NSPIRES page associated with the solicitation; anonymity of persons/institutions who submit questions will be preserved.
Chemical Evolution of the Solid Earth and Volcanology
No deadline listedU.S. National Science Foundation · Amount varies
The Chemical Evolution of the Solid Earth and Volcanology (CESEV) program aims to advance fundamental knowledge about the origin and evolution of our home planet including its core, mantle, and continental crust. The program encourages a wide range of laboratory, field, experimental, theoretical, and/or computational studies that explore the continuous high-temperature igneous and metamorphic geochemical and petrologic processes that shape the Earth. Volcanology and magmatic processes, ore deposits and economic geology, and geochronology are all in the purview of this program. Research in these areas can help improve our understanding of volcanic and other natural hazards, and the distribution of mineral and other natural resources.
Education Programs in Atmospheric and Geospace Sciences
No deadline listedU.S. National Science Foundation · Amount varies
AGSEducation supports efforts to integrateatmospheric and geospaceresearch and education via two main program areas, which are: 1) Research Experiences for Undergraduates (REU) Site Program . This program provides funding to Universities andResearch Laboratories that allows them to offer summer internships to undergraduate students who would like to participate inatmospheric and/or geospaceresearch efforts. Proposals may be submitted annually (August deadline). 2) AGS Postdoctoral Fellowships :AGS awards 2-year Postdoctoral Fellowships to highly qualified investigators within 3 years of obtaining their PhD to carry out an integrated program of independent research and education. While the postdoc program is funded by core programs, the AGS Education program supports the cost of professional development for the fellows. Additionally, this program will support efforts related to education and professional development for undergraduate and graduate students and postdocs within the NSF Atmospheric and Geospace communities.Proposals to the AGS Education program are acceptedby invitation only. Please contact theeducation program director if you intend to submit a proposal to this program.
Multilateral Partnerships Leveraging Excellence
No deadline listedU.S. National Science Foundation · From $200K
Many of the most pressing challenges in research and innovation require collaboration across national and disciplinary boundaries to achieve important advances. A growing number of topics are best addressed on a multilateral basis, building partnerships that leverage diverse expertise, data, infrastructure, and perspectives to advance understanding on critical topics of regional or global importance. At the same time, funders, research organizations, and researchers alike typically have limited experience with multilateral partnerships. The Office of International Science and Engineering’s MultiPLEx program seeks to support visionary, and ambitious international multilateral research partnerships that are required to hasten progress in addressing grand challenges by leveraging research excellence in the U.S. and around the globe. The program also seeks to advance understanding of effective multilateral collaboration. MultiPLEx welcomes proposals that Address urgent research and/or societal challenge of global importance (including but not limited to critical and emerging technology research) and require an inherently international multilateral approach to achieve impactful research results, partnering with at least two countries other than the U.S. Proposals that engage partners across distinct geographic regions are an area of interest. Make clear how the proposed international collaboration will enable research advances and broader impacts that go beyond what can be accomplished by a narrower team. Include a diverse group of U.S. institutions and/or individuals, leveraging the full range of talent that society has to offer MultiPLEx funds support the U.S. research team. Research partners should seek funding from their own national funding agencies or from other sources. A typical MultiPLEx award will be up to three years in duration. The MultiPLEX program is not intended to replace existing OISE or directorate programs. Proposals submitted to MultiPLEX must fall outside the scope of existing OISE or directorate programs. Any proposal submitted to MultiPLEx that is not responsive to this Program Description may be transferred to another OISE program or returned without review. OISE may periodically issue a Dear Colleague Letter inviting MultiPLEx proposals in specific priority areas. PIs interested in submitting proposals that do not respond to a DCL are strongly encouraged to consult a MultiPLEx program director prior to submission to confirm appropriateness. Unless specified in a DCL, MultiPLEx proposals may be submitted any time.
Long Range Broad Agency Announcement (BAA) for NSWC Crane
No deadline listedNSWC CRANE - N00164 · Amount varies
This announcement seeks revolutionary research ideas, and technology demonstrators that offer potential for advancement and improvement of NSWC Crane’s primary mission areas. NSWC Crane is a field activity of the Naval Sea Systems Command. NSWC Crane supports a wide range of government agencies in the interest of national security. NSWC Crane may publish BAAs and other solicitations in response to specific needs. This BAA is issued to seek innovative solutions and ideas for topics not covered via other means. It is strongly encouraged that potential proposers review existing NSWC Crane solicitations to avoid duplication of effort and to contact the identified points of contact for each BAA topic to discuss specific details of the needs. The mission of NSWC Crane is to provide research, development, test and evaluation, acquisition engineering, in-service engineering and technical support in its assigned technical capabilities for the United States Navy, Department of Defense components and agencies, and other federal agencies and components engaged in national security. NSWC Crane also works to apply component and system-level product and industrial engineering to surface sensors, strategic systems, special warfare devices and electronic warfare systems, as well as to execute other responsibilities as assigned by the Commander, Naval Surface Warfare Center. The focus of NSWC Crane is “Harnessing the Power of Technology for the Warfighter.” Crane specializes in total lifecycle support in three broad focus areas: Expeditionary Warfare, Strategic Missions, and Electronic Warfare, which support ten assigned technical capabilities (TCs) listed below. 1. Electronic Warfare (EW) 2. Infrared and Pyrotechnic Countermeasures 3. Strategic Systems Hardware 4. Expeditionary Warfare and Systems 5. Advanced Electronics 6. Sensors and Surveillance Systems 7. Hypersonic Weapon Systems 8. Power and Energy Systems 9. Electro-optic and Infrared Technologies 10.Force level EW Mission Analysis, Advanced Concepts and Technologies Within each of the TCs, there are multiple thrust areas, which present considerable opportunities for innovative research and solutions to support national security imperatives. There is intentional overlapping space within the listed TC such that a potential technology or research idea may support multiple TCs. Any proposal should list the principal TC as well as any adjunct TCs that should be considered. Proposals that support multiple TCs are strongly desired but not necessary.
NSF National Innovation Corps Teams (NSF National I-Corps (TM) Teams) program
No deadline listedU.S. National Science Foundation · From $50K
The U.S. National Science Foundation (NSF) continues to develop and nurture a national innovation ecosystem that guides the output of scientific discoveries closer to the development of technologies, products, processes, and services that benefit all Americans . The goals of the NSF I-Corps ™ p rogram are to spur translation of foundational research to the marketplace, to encourage collaboration between academia and industry, and to train NSF-funded faculty, students and other researchers in innovation and entrepreneurship skills. The NSF National I-Corps program utilizes experiential learning of customer and industry discovery, coupled with first-hand investigation of industrial processes, to quickly assess the translational potential of inventions. The NSF National I-Corps program is designed to support the commercialization of "deep technologies,” those revolving around foundational discoveries in science and engineering. The NSF National I-Corps program addresses the skill and knowledge gaps associated with the transformation of basic research into deep technology ventures (DTVs). The purpose of the NSF National I-Corps Teams program is to provide NSF-funded researchers additional support in the form of entrepreneurial education, mentoring, and funding to accelerate the translation of knowledge derived from foundational research into emerging products, processes, and services that may attract subsequent third-party funding. The outcomes of NSF National I-Corps Teams' projects are threefold: 1) a decision on a clear path forward based on an assessment of the business model, 2) substantial first-hand evidence for or against product-market fit, with the identification of customer segments and corresponding value propositions, and 3) a narrative of a technology demonstration for potential partners.
Environmental Engineering
No deadline listedU.S. National Science Foundation · Amount varies
The Environmental Engineering program is part of the Environmental Engineering and Sustainability cluster, which also includes 1) the Nanoscale Interactions program; and 2) the Environmental Sustainability program. Environmental engineering is an interdisciplinary field that applies chemical, biological, and physical scientific principles to protect human and ecological health. The goal of the Environmental Engineering program is tosupport potentially transformative fundamental research that applies scientific and engineering principles to 1) prevent, minimize, or re-use solid, liquid, and gaseous discharges of pollution to soil, water, and air by closing resource loops or through other measures; 2) mitigate the ecological and human-health impacts of such releases by smart/adaptive/reactive amendments or manipulation of the environment, and 3) remediate polluted environments through engineered chemical, biological, and/or geo-physical processes. Integral to achieving these goals is a fundamental understanding of the transport and biogeochemical reactivity of pollutants in the environment. Therefore, research on environmental micro/biology, environmental chemistry, and environmental geophysics may be relevant providing the research has a clear objective of protecting human and ecological health. Major areas of interest include (but are not limited to): Building afuture without pollution or waste: Investigation of innovative biogeochemical processes that prevent or minimize the production of waste; waste valorization and other research that will lead to new technologies toextract resources from waste streams to close the resource loop. Sustainable supply and protection ofwater: Investigation of innovative biogeochemical processesthat remove, biologically or chemically transform, and/or prevent therelease of contaminants in surface and groundwater; innovative processesfor recovery of water, nutrients, and other resources from wastewater,saline water, or brines; innovative approaches to smart and adaptive management of surface water, groundwater, and urban watersheds and storm water to maintain/improve quality and prevent downstream impacts from nutrients and other water constituents. Environmentalchemistry, fate, and transport of nutrients and contaminants of emergingconcern in air, water, soils, and sediments:Investigation of transport and biogeochemical reactivity in theenvironment; environmental forensics to identify sources and reaction pathways; field- and laboratory scale experimental research that bridgesgaps between data and predictions from molecular, continuum, and field-scale modeling. Environmentalengineering of the built environment: Research to understand the biogeochemical reactivity of the builtenvironment with the goal of enhancing and improving human and ecological health; research that will lead to new technologies to improve outdoor and indoor air quality; research to understand how drinking water and wastewater chemical characteristics and microbial community structure impact or are affected by water quality and human health. NOTE: Proposals with a scientific focus on chemical or physical separation processes (for example, materials or processes for reverse osmosis, membrane distillation, and hypo-filtration) should be submitted to the Interfacial Engineering program (CBET 1417). Proposals that seek to advance fundamental and quantitative understanding of the behaviors of nanomaterials and nanosystems should be submitted to the Nanoscale Interactions program (CBET 1179). Proposals focused on in vitro molecular-level environmental chemistry research should be submitted to Environmental Chemical Sciences program (CHE-ECS 6882). Proposals focusing on industrial ecology, green engineering, and ecological/earth systems engineering should be submitted to the Environmental Sustainability program (CBET 7643). Proposals whose main research focus is on materials development, sensors, or environmental monitoring that do not seek to understand biogeochemical reactivity mechanisms or treatment efficiency are not encouraged and may be returned without review. Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the program director to avoid the possibility of the proposal being returned without review. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate.Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged.Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals . Compliance: Proposals that are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.
Mind, Machine and Motor Nexus
No deadline listedU.S. National Science Foundation · Amount varies
The Mind, Machine, and Motor Nexus (M3X) program supports fundamental research that enables intelligent engineered systems and humans to engage in bidirectional interaction in a physics-based environment, to enhance and ensure safety, productivity, and well-being. For the purpose of this program an intelligent engineered system is a human-designed system — physical, virtual, or a combination of both — that interacts with its environment to achieve specific goals. These systems collect data, analyze it to make informed decisions, and take actions that enhance safety, efficiency, and well-being. They may operate autonomously or collaboratively with humans, adapting their actions based on the data they collect. A key requirement for the M3X program is that these systems must function within a physics-based environment, whether physical or virtual, where interactions exhibit recognizable physical behaviors, such as those associated with gravity, friction, force, and inertia. Intelligent engineered systems are becoming increasingly integrated into our daily lives, interacting with humans across diverse environments and through different modalities (for example, visual, haptic, auditory). M3X aims to deepen the understanding of such interactions, particularly in complex and dynamic settings such as elder care, disaster response, and dynamic workplaces. The program encourages explorations into the physical or cognitive principles that enable or constrain human-machine collaboration, advancing foundational theories, interaction modeling, and technological innovations that enhance adaptability, efficiency, and intuitiveness. Proposals submitted to the M3X program must clearly articulate how the proposed work advances knowledge of bidirectional interactions between humans and intelligent engineered systems. Examples include robots assisting in disaster response, smart environments that learn user preferences, and virtual reality-based rehabilitation technologies that simulate plausible physics. While proposals are not required to address all aspects of the interaction, they must propose significant contributions to at least one of the following areas: Conceptual Frameworks and Theoretical Modeling Development of new conceptual, mathematical, or computational frameworks that provide structured approaches to understanding and analyzing the bidirectional interaction between humans and engineered systems. These frameworks serve as formalized models or methodologies that guide research in areas such as cognition, perception, and behavior of both humans and intelligent engineered systems during their interactions. Additionally, these computational frameworks facilitate the modeling of safe operating conditions in dynamic task environments and the identification of theoretical limits of cognitive and physical performance capabilities during interaction. Dynamic Interaction Analysis and Simulation Investigation of emerging and established bidirectional interaction phenomena in physical, virtual, or hybrid environments. Potential topics may include learning, co-adaptation, cooperation, competition, and multi-scale interaction. The program also welcomes novel experimental paradigms to evaluate processes and performance. Innovative Technologies for Enhanced Interaction Development of methods, tools, and technologies to enable novel or improved forms of bidirectional interaction, guided by hypotheses and interaction-driven requirements. Potential topics may include creating meaningful task environments (physical, virtual, or hybrid); designing new modalities and interfaces for interaction; developing advanced evaluation, measurement, and instrumentation methods; testbeds, and improving real-time integration of multi-modal sensorimotor data. The M3X program strongly encourages proposals that aim to establish new perspectives and paradigms across one or more of the three areas listed above . To ensure strong alignment with M3X objectives, Principal Investigators are encouraged to submit a one-page Project Summary to M3X@nsf.gov for feedback from Program Directors.
Infrastructure Innovation for Biological Research
No deadline listedU.S. National Science Foundation · $300K–$800K
The Infrastructure Innovation for Biological Research Program (Innovation) supports research to design novel or greatly improved research tools and methods that advance contemporary biology in any research area supported by the Directorate forBiological Sciences at NSF. The Innovation Program focuses on research infrastructure that is broadly applicable to researchers in three programmatic areas: Bioinformatics, Instrumentation, and Research Methods. Infrastructure supported by this program is expected to advance biological understanding by improving scientists’ abilities to manipulate, control, analyze, or measure critical aspects of biological systems, which can be essential for addressing important fundamental research questions. Proposals submitted to these programmatic areas can do one of three things to advance or transform research in biology: develop novel infrastructure, significantly redesign existing infrastructure, or adapt existing infrastructure in novel ways. Projects are expected to have a significant application to one or more biological science questions and have the potential to be used by a community of researchers beyond a single research team. Please refer to the descriptions of individual programmatic areas for detailed guidance on what is supported through this solicitation (see links below).