Browse grants

National Institutes of Health · Amount varies

The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to advance the program's mission of accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.All of Us partnered research studies are collaborative initiatives funded by a study sponsor external to All of Us to collect and add new data to the All of Us Researcher Workbench in accordance with All of Us" best practices. All of Us partnered research studies are open to the broad scientific community and require investigators to apply for and receive an X01 award under this announcement.This will enable longitudinal follow‐up and repeat sampling, and provide multiomic data (genomics, proteomics, metabolomics, and other high‐dimensional molecular profiles), integrated clinical, environmental, and life‐course data, infrastructure designed to support future clinical‐trial recruitment, and public‐private partnership pathways.This opportunity will enable researchers to conduct assays to evaluate associations between newly collected and existing All of Us data and add new data to the All of Us dataset for broad use by the research community. High-priority areas for biospecimen analyses may include, but are not limited to, large scale projects that propose integrated multiomics analyses, early disease detection, biomarker discovery or validation, novel risk models for incident disease, and/or novel disease stratification for chronic disease risk, diagnosis, and prognosis, in support of advancing precision medicine. For more information, please visit the All of Us X01 Partnered Research Studies Resource webpage.

U.S. National Science Foundation · Amount varies

The MCA program offers an opportunity for scientists and engineers at the mid-career stage (see restrictions under Additional Eligibility Information) to substantively enhance and advance theirresearch program and career trajectory. Mid-career scientists are at a critical career transition stage where they need to advance their research programs to ensure long-term productivity and creativity but are often constrained by service, teaching, or other activities that limit the amount of time devoted to research. The MCA program provides protected time, resources, and the means to gain new skills through synergistic and mutually beneficial partnerships, typically at an institution other than the candidate's home institution. Partners from outside the Principal Investigator's (PI) own subdiscipline or discipline are encouraged, but not required, to enhance interdisciplinary networking and convergence across science and engineering fields. Research p rojects that envision new insights on existing problems or identify new problems made accessible with cutting-edge methodology or expertise from other fields are encouraged . A key component of a successful MCA will be the demonstration that the PI's currentresearch program could substantively benefit from the protected time, mentored partnership(s), and resources provided through this program, such thatthere is a substantial enhancement to the PI's research and career trajectory, enabling scientific and academic advancementnot likely without this support. The MCA is the only cross-directorate NSF program specifically aimed at providing protected time and resources to established scientists and engineers targeted at the mid-career stage.Participating programs in the Directorates for Biological Sciences (BIO), Geosciences (GEO), Social, Behavioral and Economic Sciences (SBE), and Education and Human Resources (EHR) will accept MCA proposals. To help identify the disciplinary program in which the MCA should be reviewed, PIs are urged to investigate the research areas supported by the different directorates and participating programs. PIs are strongly encouraged to discuss the suitability of their MCA proposal with a Program Officer from the appropriate directorate (see https://new.nsf.gov/funding/opportunities/mca-mid-career-advancement/announcements/111199 ).PIs from EPSCoR jurisdictions are especially encouraged to apply.

U.S. National Science Foundation · $1M–$5M

The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with an S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. Recognizing that financial aid alone cannot increase retention and graduation in STEM, the program provides awards to institutions of higher education (IHEs) not only to fund scholarships, but also to adapt, implement, and study evidence-based curricular and co-curricular [a] activities that have been shown to be effective in supporting recruitment, retention, transfer (if appropriate), student success, academic/career pathways, and graduation in STEM. To be eligible, scholars must be domestic low-income students with academic ability, talent, or potential and demonstrated unmet financial need who are enrolled in an associate, baccalaureate, or graduate degree program in an S-STEM eligible discipline. Proposers must provide an analysis that articulates the characteristics and academic needs of the population of students they are trying to serve. NSF is particularly interested in supporting the attainment of degrees in fields identified as critical needs for the Nation. It is up to the proposer to make a compelling case that such a field serves a critical need in the United States. [a] an activity at a school or college pursued in addition to the normal course of study. S-STEM Eligible Degree Programs Associate of Arts, Associate of Science, Associate of Engineering, and Associate of Applied Science Bachelor of Arts, Bachelor of Science, Bachelor of Engineering and Bachelor of Applied Science Master of Arts, Master of Science, and Master of Engineering Doctoral (Ph.D. or other comparable doctoral degree) S-STEM Eligible Disciplines Disciplinary fields in which research is funded by NSF, including technology fields associated with the S-STEM-eligible disciplines (e.g., biotechnology, chemical technology, engineering technology, information technology, etc.). The following degrees and disciplines areexcluded: Clinical degree programs, including medical degrees, nursing, veterinary medicine, pharmacy, physical therapy, and others not funded by NSF, are ineligible degrees. Programs for STEM teacher certification or licensure currently covered by the Robert Noyce Teacher Scholarship program (NOYCE) are ineligible for S-STEM funding. Business school programs that lead to Bachelor of Arts or Science in Business Administration degrees (BABA/BSBA/BBA) are not eligible for S-STEM funding. Masters and Doctoral degrees in Business Administration are also excluded. Proposers are strongly encouraged to contact Program Officers before submitting a proposal if they have questions concerning degree or disciplinary eligibility. The S-STEM program particularly encourages proposals from 2-year institutions, predominately undergraduate institutions, and urban, suburban, and rural public institutions.

U.S. National Science Foundation · $100K–$750K

The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program supports research to increase our understanding of the behavior of atmospheric regions from the middle atmosphere upward through the thermosphere and ionosphere into the exosphere. Projects explore coupling, energetics, chemistry, and dynamics on regional and global scales. The research topics include investigations of upper atmosphere responses due to a) processes driven by the lower atmospheric perturbations and (b) solar radiation and particle inputs from above. The activities supported by this program include observations from ground-based and space-based platforms, as well as theory and modeling of the upper atmosphere of the Earth and other planets in our solar systems. Novel approaches that include AI and ML tools and open data and open science practices are encouraged.

National Institutes of Health · Amount varies

This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-24-208, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V. Application Review Information of the funding opportunity are the only changes that have been made. All other aspects of this funding opportunity remain the same.

National Institutes of Health · Up to $1.5M

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

National Institutes of Health · Amount varies

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.

National Institutes of Health · Up to $500K

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

National Institutes of Health · Amount varies

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

National Institutes of Health · Up to $500K

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood. While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic cardiomyopathy play a major role in morbidity and mortality among these patients. Currently, no therapies are specifically approved to prevent or treat these common and severe cardiovascular issues in T1D. The purpose of this NOFO is to promote collaborative and interdisciplinary research aimed at enhancing the understanding of the development of CVD in individuals with T1D and the differences with CVD in T1D by continuing the efforts of the CaRe-T1D consortium.This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.

National Institutes of Health · Amount varies

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Munitions Directorate · Up to $750M

Broad Agency Announcement for Air Delivered Effects - Amendment 5

U.S. National Science Foundation · $300K–$1M

The Innovations in Graduate Education (IGE) Program is designed to encourage development and implementation of bold, new, and potentially transformative approaches to STEM graduate education training. The program seeks proposals that a) explore ways forgraduate students in STEM master’s and doctoral degree programs to develop the skills, knowledge, and competencies needed to pursue a range of STEM careers, or b) support research on the graduate education system and outcomes of systemic interventions and policies. IGE projects are intendedto generate the knowledge required for the customization, implementation, and broader adoption of potentially transformative approaches to graduate education. The program supports piloting, testing, and validating novel models or activities and examining systemic innovations with high potential to enrich and extend the knowledge base on effective graduate education approaches. The program addresses both workforce development, emphasizing broad participation, and institutional capacity-building needs in graduate education. Strategic collaborations with the private sector, non-governmental organizations (NGOs), government agencies, national laboratories, field stations, teaching and learning centers, informal science organizations, and academic partners are encouraged.

U.S. National Science Foundation · From $15M

The far-reaching impact and rate of innovation in the computer and information science and engineering fields has been remarkable, generating economic prosperity and enhancing the quality of life for people throughout the world. More than a decade ago, the National Science Foundation’s (NSF) Directorate for Computer and Information Science and Engineering (CISE) established the Expeditions in Computing (Expeditions) program to build on past successes and provide the CISE research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to define the future of computing and information. In planning Expeditions projects, investigators are strongly encouraged to come together within or across departments or institutions to combine their creative talents in the identification of compelling, transformative research agendas that look ahead by at least a decade and promise disruptive innovations in computer and information science and engineering for many years to come. Now funded at levels up to $15,000,000 for seven years, Expeditions projects represent some of the largest single investments currently made by the CISE directorate. Together with the Science and Technology Centers and the National Artificial Intelligence Research Institutes that CISE supports, Expeditions projects form the centerpiece of the directorate's center-scale award portfolio. With awards funded at levels that promote the formation of large research teams, CISE recognizes that concurrent research advances in multiple fields or sub-fields are often necessary to stimulate deep and enduring outcomes. The awards made in this program will complement research areas supported by other CISE programs, which target particular computer and information science and engineering fields. Additionally, CISE offers Innovation Transition (InTrans) awards for teams nearing the end of their Expeditions as well as Secure and Trustworthy Cyberspace (SaTC) and Cyber-Physical Systems (CPS) Frontier projects. The goal of InTransis to continue the long-term vision and objectives of CISE’s center-scale projects. Through InTrans awards, CISE will provide limited funds to match industry support.

Dept of the Army -- Materiel Command · Amount varies

The U.S. Military Academy at West Point's mission is "to educate, train, and inspire the Corps of Cadets so that each graduate is a commissioned leader of character committed to the values of Duty, Honor, Country and prepared for a career of professional excellence and service to the Nation as an officer in the United States Army." The United States Military Academy is located at West Point, New York. USMA executes research to enhance the education of cadets, develop the faculty professionally, and address important issues facing the Army and the Nation. In addition, the Academy conducts research and analysis in emerging fields that may realize novel or vastly improved Army capabilities. At West Point, research is organized and administered through centers and institutes, most of which reside within academic departments. These centers and institutes, affiliated with each other through the Academy Research Council (ARC), coordinated and supported by the Academic Research Division (ARD), provide the infrastructure necessary to tackle the nation’s and the world’s most challenging problems. Our research centers and institutes bring context to the classroom, are central to our vibrant and pioneering faculty, and are one way West Point connects to the Army and to the Nation. Our students are driven, our faculty is world-class, and through our centers, scholars and scientists thrive and produce their best work. Cadets regularly win Best Paper Awards at national and international graduate-level conferences, our faculty hold fellowships and chairmanships in their discipline's national organizations and our products are deployed to the soldier. In addition to applied research, there are centers and institutes at West Point that focus on other aspects of the USMA mission. The USMA BAA identifies topics of interest to the USMA departments, directorates, and research centers and institutes. These groups focus on executing in-house research programs, with a significant emphasis on collaborative research with other organizations. The groups fund a modest amount of extramural research in certain specific areas, and those areas are described in this BAA. The USMA BAA seeks proposals from institutions of higher education, nonprofit organizations, state and local governments, foreign organizations, foreign public entities, and for-profit organizations (i.e., large and small businesses) for research based on the following campaigns: Socio-Cultural; Information Technology; Ballistics, Weapons, and Protections; Energy and Sustainability; Materials, Measurements, and Facilities; Unmanned Systems and Space; Human Support Systems; and Artificial Intelligence, Machine Learning, and Quantum Technologies. Proposals are sought for cutting-edge innovative research that could produce discoveries with a significant impact to enable new and improved Army technologies and related operational capabilities and related technologies. The specific research areas and topics of interest described in this document should be viewed as suggestive, rather than limiting.

Food and Drug Administration · $0–$300K

The purpose of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally integrated animal food safety system providing state animal food regulatory programs the ability to achieve full implementation of the Animal Food Regulatory Program Standards (AFRPS) within 5 years and to maintain full implementation. This NOFO will also fund optional projects for state animal food regulatory programs to: Advance food safety and protect public health by strengthening partnerships with the FDA and other state animal food regulatory partners through sharing, collaboration, coordination, and leveraging each other’s expertise, work, data, and enforcement actions. Develop and standardize processes, procedures, systems, and other methods to integrate federal and state animal food regulatory work resulting in mutual reliance. Specific outcomes may include, but are not limited to: State animal food regulatory programs will achieve and maintain implementation of the AFRPS, which is recognized as a critical element to creating a national, fully integrated food safety system. Operational use of standardized animal food regulatory systems developed by state programs to compel federal reliance on state regulatory work and resources and reciprocal state reliance on federal work and resources, resulting in mutual reliance. This project will strengthen and improve FDA efforts to build an integrated food safety system by building high quality state animal food regulatory programs that can promote regulatory compliance and prevent foodborne illnesses.

Food and Drug Administration · $0–$200K

This Funding Opportunity Announcement (FOA) issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), builds upon the National Antimicrobial Resistance Monitoring System (NARMS) which was initiated in 1996 as one of the key activities in a national action plan to combat antibiotic resistance threats. The purpose of this FOA is to protect and promote public health by enhancing, strengthening, and sustaining antibiotic resistance surveillance in retail food specimens within the NARMS program. The NARMS cooperative agreement is intended to improve the detection of antibiotic resistance among bacteria in food commodities, as well as expand to new sites to expand the scope of sampling. Measurable outcomes of the program will be in alignment with the NARMS Objectives.

National Institutes of Health · Amount varies

The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.

National Institutes of Health · Amount varies

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

U.S. National Science Foundation · Amount varies

The National Quantum Initiative (NQI) Act 1 aims to ensure the continuing leadership of the United States (U.S.) in quantum information science and technology. In conformance with the NQI goals, an argument 2-5 was set forth for a renewed emphasis on identifying and fostering early adoption of quantum technologies to transform the field of Quantum Information Science and Engineering (QISE) and to accelerate broader impacts on society. A systematic approach to maturing quantum technology platforms by integrating end-users and potential customers from other fields of science and engineering and other sectors of the economy into cycles of research, development, and demonstration should lower the barriers for end-users to pioneer new applications. NSF support for use-inspired and translational research in QISE, combined with continued strong support of the underlying foundational research, is anticipated to accelerate development of a market for quantum technologies. With this program solicitation, the Foundation is taking the next step in implementing the National Quantum Virtual Laboratory (NQVL) concept as an overarching shared infrastructure designed to facilitate the translation from basic science and engineering to the resultant technology, while at the same time emphasizing and advancing its scientific and technical value. The NQVL aims to develop and utilize use-inspired and application-oriented quantum technologies. In the process, NQVL researchers will explore quantum frontiers 6 , foster the development of QISE education and workforce development strategies, engage in outreach activities at all levels, and promote input and participation from the full spectrum of talent in QISE, thereby lowering barriers at all entry points of the research enterprise. Engagement with all sectors of the United States (U.S.) QISE community will be necessary for this initiative to succeed, and, indeed, the project is designed to include participation from a full spectrum of organizations who have expertise to contribute. In particular, NSF recognizes that the involvement of industry partners is essential and will welcome these to be a part of the overall structure. Partnerships with other U.S. Federal agencies under the NQI umbrella are also encouraged. While this solicitation lays out the vision for the entire NQVL program that includes Quantum Science and Technology Demonstration (QSTD) projects, support for enabling technologies through Transformative Advances in Quantum Systems (TAQS), as well as a central coordination hub, only proposals for Design- and Implementation-phase QSTDs are solicited at this time. Submission of a QSTD:Design proposal is contingent upon the existence of a QSTD:Pilot project in the same topical area, and the positive recommendation from the Conceptual Design Review of the QSTD:Pilot project. The QSTD:Design project builds on progress made in the QSTD:Pilot phase. Submission of a QSTD:Implementation proposal is contingent upon the existence of a QSTD:Design project in the same topical area, and the positive recommendation from the Preliminary Design Review of the QSTD:Design project. The QSTD:Implementation project builds on progress made in the QSTD:Design phase. It is required that prospective PIs contact the NQVL Program Officer(s) as soon as possible, but not later than two weeks before submitting a proposal in response to this solicitation, to ascertain that the focus and budget of their proposal is appropriate for this solicitation. H.R.6227 - National Quantum Initiative Act, https://www.congress.gov/bill/115th-congress/house-bill/6227 Accelerating Progress Towards Practical Quantum Advantage, A National Science Foundation Project Scoping Workshop (2022), https://arxiv.org/abs/2210.14757 Quantum Computer Systems for Scientific Discovery, PRX Quantum 2, 017001 (2021) https://doi.org/10.1103/PRXQuantum.2.017001 Development of Quantum InterConnects for Next-Generation Information Technologies, PRX Quantum 2, 017002 (2021) https://doi.org/10.1103/PRXQuantum.2.017002 Quantum Simulators: Architectures and Opportunities, PRX Quantum 2, 017003 (2021) https://doi.org/10.1103/PRXQuantum.2.017003 Quantum Frontiers: Report on Community Input to the Nation's Strategy for Quantum Information Science, https://www.quantum.gov/wp-content/uploads/2020/10/QuantumFrontiers.pdf