Browse grants

National Institutes of Health · Amount varies

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIH Science Education Partnership Award (SEPA) program is to support educational activities that increase understanding of biomedical research among pre-college (pre-kindergarten to grade12) individuals, and to encourage awareness of and continued interest in careers in science, technology, engineering, and mathematics (STEM).

National Institutes of Health · Amount varies

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; andFoster a better understanding of biomedical, behavioral and clinical research and its implications.

National Institutes of Health · Up to $500K

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

National Institutes of Health · Amount varies

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) encourages grant applications to support research in cancer epidemiology cohort studies that address specific knowledge gaps in cancer etiology and survivorship. Applications should include hypothesis-based research, support for cohort infrastructure and/or maintenance, continued follow-up, and sharing of data and biospecimen resources as appropriate.

National Institutes of Health · Up to $500K

This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal hypotheses may include biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, and comorbidity factors that individually, sequentially, or in combination trigger human behaviors and oral-systemic health outcomes, with impacts that may be direct or traceably distal. Applications that propose projects to develop or refine causal hypotheses also are encouraged.

National Institutes of Health · Amount varies

This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, include mechanistic studies. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities. Support is available for clinical trials up to 5 years, as well as for extended clinical trials of 6- or 7-years.Investigators are encouraged to visit this NIH website for additional information about the overall mission and research areas of NIAID.Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation Cooperative Agreement (U01) application. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.

National Institutes of Health · Up to $500K

This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens.

National Institutes of Health · Amount varies

The purpose of the Academic Career Excellence (ACE) Award (K32) is to support rigorous, mentored scientific research and career development for up to three years for early-stage postdoctoral scholars. Candidates must submit their application up to one year prior to beginning their postdoctoral position or no more than two years after their postdoctoral training begins (resubmissions included). The ACE K32 will foster early, goal-directed planning and encourage innovative applications with the potential for a significant impact on scientific research and career development. Inclusion of preliminary data are not required as the ACE K32 emphasizes innovative research ideas and thoughtful plans for training and mentorship that will facilitate the development of the postdoctoral scholars who have the potential to become productive, independent investigators in research fields relevant to the missions of the participating NIH Institutes and Centers.

National Institutes of Health · Amount varies

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) announces a program that provides NIAMS-supported K01, K08, K23, and K25 recipients the opportunity to apply for the Small Grant (R03) during the second to fourth year of their K award, as well as to provide support to recipients of significant career development awards from federal or non-federal organizations that are focused on the NIAMS' mission areas. Through this mechanism, which allows up to $50,000 direct costs per year for up to two years, the NIAMS is seeking to enhance the capability of scientists to conduct research as they transition to fully independent investigator. The R03 grant mechanism allows support of different types of projects, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. In addition to the existing career development awards, the R03 is intended to support short term research projects to enable opportunities for a subsequent R01, or equivalent, application. Clinical trials of any phase will not be supported by this NOFO.This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Air Force -- Research Lab · $0–$49M

Original Solictation: Closing Date of the FOA FROM: 18 July 2024 TO: 18 July 2029 Cost Ceiling $49M Contracting/Agreements Points of Contact (POC) Agreements Officer Mariah Salazar Agreements Specialist Monique Esquibel-Sena Emails: mariah.salazar@us.af.mil; monique.esquibel_sena@us.af.mil Solicitation Amend 1: Closing Date of the FOA FROM: 18 July 2024 TO: 18 July 2029 Cost Ceiling $49M Contracting/Agreements Points of Contact (POC) Agreements Officer Mariah Salazar Agreements Specialist Monique Esquibel-Sena Emails: mariah.salazar@us.af.mil; monique.esquibel_sena@us.af.mil (Revisions made: Updated information on Mandatory Letter of Intent to allow for interested parties to submit Letters of Intent through Valid Eval portal) Solicitation Amend 2: Closing Date of the FOA FROM: 18 July 2024 TO: 18 July 2029 Cost Ceiling $49M Contracting/Agreements Points of Contact (POC) Agreements Officer Mariah Salazar Agreements Specialist Monique Esquibel-Sena Emails: mariah.salazar@us.af.mil; monique.esquibel_sena@us.af.mil (Revisions made: Added detail for Letter of Intent Evaluation Criteria) Solicitation Amend 3: Closing Date of the FOA FROM: 18 July 2024 TO: 18 July 2029 Cost Ceiling $49M Contracting/Agreements Points of Contact (POC) Agreements Officer Mariah Salazar Alternate Agreements Officer Jennifer Jaramillo Agreements Specialist Monique Esquibel-Sena Brendan Merritt Emails: mariah.salazar@us.af.mil; monique.esquibel_sena@us.af.mil, jennifer.jaramillo@us.af.mil , brendan.merritt@us.af.mil (Revisions made: Changed Letter of Intent review from 10 business days to 30 business days, Added verbiage to Section, D. Review and Selection Process, on Security Risk Review, added Agreement Specialist, Brendan Merritt, brendan.merritt@us.af.mil) Solicitation Amend 4: Closing Date of the FOA FROM: 18 July 2024 TO: 18 July 2029 Cost Ceiling $49M Contracting/Agreements Points of Contact (POC) Agreements Officer Mariah Salazar Alternate Agreements Officer Jennifer Jaramillo Agreements Specialist Monique Esquibel-Sena Emails: mariah.salazar@us.af.mil; monique.esquibel_sena@us.af.mil, jennifer.jaramillo@us.af.mil (Revisions made: Changed Attachment 2 of Solicitation to DoD R&D General Terms and Conditions MARCH 2025. Removed Agreement Specialist, Brendan Merritt, brendan.merritt@us.af.mil)

Air Force -- Research Lab · Up to $99M

“No submissions through Grants.gov will be accepted. All submissions must follow SAM.gov instructions. For full opportunity announcement see SAM.gov link below". https://sam.gov/opp/7aca91ca2c5842ed9898b5226493ab85/view

Advanced Research Projects Agency Energy · $5M–$20M

The purpose of this modification is to clarify the meaning of the Program Policy Factors in Section V.C. To obtain a copy of the Notice of Funding Opportunity (NOFO) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this NOFO, Applicants must register with and submit application materials through ARPA-E eXCHANGE ( https://arpa-e-foa.energy.gov/Registration.aspx ). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with NOFO name and number in the subject line). Questions about this NOFO? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq . For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. AGENCY OVERVIEW The Advanced Research Projects Agency – Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that— (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.” ARPA-E issues this Notice of Funding Opportunity (NOFO) under its authorizing statute codified at 42 U.S.C. § 16538. The NOFO and any cooperative agreements or grants made under this NOFO are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established “learning curves” where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. In contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E will provide support at the highest funding level only for submissions with significant technology risk, aggressive timetables, and careful management and mitigation of the associated risks. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive – that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development (R&D). The Office of Management and Budget defines “applied research” as an “original investigation undertaken in order to acquire new knowledge…directed primarily towards a specific practical aim or objective” and defines “experimental development” as “creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes.”0F1 Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as “experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts”)1 should contact the DOE’s Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R&D for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). ARPA-E encourages submissions stemming from ideas that still require proof-of-concept R&D efforts as well as those for which some proof-of-concept demonstration already exists. Submissions can propose a project with the end deliverable being an extremely creative, but partial solution. PROGRAM OVERVIEW The Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary focus on early-stage transformational energy technologies that require proof of concept. Technologies that achieve substantial technical advancement under ARPA-E support may still face significant technical and commercial challenges upon completion of an award's funding period, and thus are at risk of being stranded in their development path once ARPA-E funding ends. Experience across ARPA-E’s diverse energy portfolios, and input from a wide range of investors and industry stakeholders, indicate that pre-commercial scaling projects are critical to establish practical performance and cost parameters. These pre-commercial scaling projects aim to 1) translate the performance achieved at bench scale to commercially scalable versions of the technology, 2) integrate the technology with broader systems, 3) provide extended performance data, and 4) validate the manufacturability and reliability of new energy technologies. Successful scaling projects should enable industry stakeholders to justify the substantial commitments of financial resources, personnel, manufacturing facilities, and materials necessary to subsequently deploy the technologies at a commercial scale. SCALEUP Ready seeks to scale the most promising technologies previously funded by ARPA-E. The possibility of ARPA-E-funded technologies becoming stranded along their development pathways leaves substantial intellectual property developed with American taxpayer dollars vulnerable to adoption by foreign competitors, who capture it for continued development and economic benefit overseas. This harms national competitiveness, as U.S. industries often fall behind on the development, scaling, and manufacturing of technologies necessary to compete in rapidly evolving global energy markets. Thus, projects selected for SCALEUP Ready will meet ARPA-E’s statutory goals by “accelerating transformational technological advances in areas that industry by itself is not likely to undertake because of technical and financial uncertainty."

National Institute of Standards and Technology · From $10M

NIST is soliciting proposals from eligible applicants for research, prototyping, and commercial solutions that advance microelectronics technology in the U.S., to be considered for funding by the CHIPS Research and Development Office (CRDO).

Munitions Directorate · Up to $750M

Broad Agency Announcement for Air Dominance. This effort was initially posted on 1 Nov 2024.

Naval Supply Systems Command · $0

This FOA is intended for proposals related to basic and applied research in the STEM categories, and not related to the development of a specific system or hardware procurement. The proposal submission process has two stages: I. Applicants are encouraged to submit a white paper first to Grants@NPS.edu, ; and II. Applicants must submit a full proposal through Grants.gov (do not submit white papers through Grants.gov, only full proposals) Applicants are encouraged to submit a White Paper in advance of a Full Proposal to minimize the labor and other costs associated with the production of detailed full proposals that have little chance of being selected for funding. Based on an assessment of the white papers, the responsible Research Program Officer will provide informal feedback notification to the prospective awardees to encourage or discourage submission proposals. The Research Program Officer may also, on occasion, provide feedback encouraging re-work to strengthen a proposal. White Papers may be submitted at any time during the open period of this FOA. A separate White Paper is required for each research proposal.

Washington Headquarters Services · $50K–$20M

See the "Related Documents" and "Package" tabs for the complete application package, including the full text of the Notice of Funding Opportunity. The Department of War (DoW) Cyber Service Academy (CSA) is authorized by Chapter 112 of Title 10, United States Code, Section 2200. The purpose of the program is to support the recruitment of new cyber talent and the retention of current highly skilled professionals within the DoW cyber workforce. Additionally, this program serves to enhance the national pipeline for the development of cyber personnel by providing grants to institutions of higher education. Regionally and nationally accredited U.S. institutions of higher education, designated under the National Centers of Academic Excellence in Cybersecurity (NCAE-C) and known as National Centers of Academic Excellence in Cyber Defense, Research, and/or Cyber Operations (hereinafter referred to as designated institutions) are invited to submit proposals for developing and managing a full-time, institution-based, grant-funded scholarship program in cyber-related disciplines for Academic Year 2026-2027. Consistent with 10 U.S.C. 2200b, proposals to this solicitation may also request modest collateral support for purposes of institutional capacity building to include faculty development, laboratory improvements, and/or curriculum development, in cyber-related topics to providing a strong foundation for a DoW CSA.

ACC APG - Natick · Amount varies

The Soldier Center is seeking solutions in the following scientific and technical areas: Combat Feeding & Equipment – Ration development, field feeding systems Soldier Protection & Survivability – Headborne protection, modular armor, chemical/biological protection, nanotechnology Modeling & Simulation – Soldier effectiveness, operational survivability Human Performance & Biomechanics – Body-worn systems, hand-held devices, soldier-centric sensors Expeditionary Maneuver Support – Energy efficiency, EMI/EMP protection, battlefield mobility Aerial Delivery – Advanced airdrop systems for personnel and cargo Simulation & Training Technology – Medical training, AI-based battlefield visualization, cyberspace warfare training This Broad Agency Announcement (BAA) is intended to fulfill requirements for scientific study and experimentation directed toward advancing state-of-the-art technologies and/or increasing knowledge and understanding as a means of eliminating current technology barriers. This BAA DOES NOT focus on specific systems or hardware solutions. This BAA identifies DEVCOM SOLDIER CENTER research/exploratory development areas of interest and provides prospective offerors information on the preparation of proposals along with proposal evaluation factors. The Government may award purchase orders, contracts, grants, cooperative agreements, or other transactions against this BAA. Read the Full BAA & Submission Guidelines: On SAM.gov https://sam.gov/opp/e8c7609f0f154df4afda846595bca888/view

Dept of the Army -- Materiel Command · $200K–$10M

The ARO is soliciting proposals for Staff Research Program opportunities. The purpose of the program is to enable ARO scientific staff to maintain and expand professional competence in support of fulfilling the ARO mission through the conduct of hands-on, basic research. The staff research will be performed collaboratively with institutions external to ARO. Staff research efforts will involve scientific study directed toward advancing the state-of-the-art or increasing knowledge and scientific understanding in engineering, physical, life and information sciences, when there is an intersection with the interests and capabilities of the participating external institutions in these basic research areas. Protection of Mission Integrity: The primary role of the ARO scientific staff is to objectively assess and fund extramural research at numerous institutions across the U.S. and throughout the world. Since it is vitally important that the ARO be impartial in its actions, ARO scientists cannot engage in activities that could compromise the perceived objectivity of that scientist with respect to the institution, or with respect to the areas of science/engineering that they are responsible for as Program Managers. Consequently, ARO Program Managers will be disqualified from taking official actions regarding any institution at which that PM conducts Staff Research. Staff research will be conducted, directed and managed by an ARO scientist at the institution's laboratory facilities or field research sites, in collaboration with a PI designated by the institution. ARO scientists will not be named as a PI on any proposal or resulting award. Results of the Staff Research Program may include publication or co-authorship of research results and presentation at scientific forums, and contribute to the education and training of students, in accordance with the terms of the cooperative agreement. NOTE: ARO scientific staff will seek out a collaborating institution to engage in staff research as opportunities arise and at the discretion of ARO.

Centers for Disease Control and Prevention - ERA · $0

Submit application as necessary for Type 6 Applications.

Centers for Disease Control and Prevention - ERA · $0

Submit application as necessary for Type 6 Applications.