Browse grants
Federal and state grant opportunities with plain-English eligibility summaries. We aggregate public records — always verify the details on the funder’s site before applying. Or browse the complete index →
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Due Aug 21, 2028National Institutes of Health · Up to $3M
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH UG3/UH3 funds discovery and development of interventions — medications and devices — to prevent and treat substance use disorders and overdose, including preclinical and clinical studies. Awards up to about $3,000,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreTransformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
Due Aug 21, 2028National Institutes of Health · Up to $500K
Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 funds development of non-invasive or minimally invasive technologies to image the human olfactory system at high resolution. Awards up to about $500,000; multidisciplinary teams are encouraged.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreVet-LIRN Capacity-Building Project and Equipment Grants (U18)
Due Sep 4, 2028Food and Drug Administration · $225K–$2.5M
This FDA grant (U18, $225,000 to $2,500,000) funds veterinary diagnostic laboratories in the Vet-LIRN network to build capacity for animal food safety and antimicrobial resistance testing, including equipment and method development. Eligibility is broad, covering nonprofits (with or without 501(c)(3) status), small businesses, for-profit organizations, universities, tribal governments, and state/local governments. No unusual disqualifiers are noted, and the deadline is not imminent.
NonprofitsSmall businessGovernment / tribalSchools & universities+2 moreLimited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)
Due Sep 25, 2028National Institutes of Health · Up to $1.8M
This NIH/NIEHS P42 grant funds Superfund Research Program Centers that combine biomedical and environmental science and engineering to study hazardous substances. By law, eligibility is limited to accredited institutions of higher education, though they may subcontract with other organizations and governments. Awards are large (up to roughly $1.75M), and foreign organizations and foreign components of U.S. organizations are not eligible to apply.
Schools & universitiesResearchersLarge awardNarrow eligibilityDrinking Water Fluoridation RFA
UnofficialDue Sep 28, 2028Department of Health · Up to $2.5M
The New York State Department of Health's Drinking Water Fluoridation RFA funds eligible NYS municipalities to plan (Component A) or implement/maintain (Component B) community water fluoridation systems, with awards up to $2,500,000, on a rolling submission basis. While listed eligibility includes for-profit, governmental, and not-for-profit entities, the program description specifically targets NYS municipalities, so applicants should confirm municipal eligibility before applying. The deadline is September 28, 2028.
NonprofitsGovernment / tribalLarge awardNarrow eligibilityOccupational Safety and Health Education and Research Centers (T42)
Due Oct 26, 2028Centers for Disease Control and Prevention - ERA · $4.5M–$9M
This CDC/NIOSH program funds academic institutions to run Education and Research Centers providing interdisciplinary training and research in occupational safety and health. Awards are large (roughly $4.5M to $9M). Eligibility is narrow: only one application per institution is allowed, and current holders of a NIOSH T03 training grant cannot receive an award or sub-award under this opportunity.
Schools & universitiesResearchersLarge awardNarrow eligibilityOccupational Safety and Health Training Project Grants (T03)
Due Oct 26, 2028Centers for Disease Control and Prevention - ERA · $50K–$550K
This CDC/NIOSH T03 program funds Training Project Grants for occupational safety and health education, mostly at academic institutions providing undergraduate, graduate, and post-graduate training, plus a limited number of non-academic awards for specialized audiences. Awards range from roughly $50,000 up to about $550,000. Foreign organizations are not eligible to apply.
Schools & universitiesResearchersLarge awardThe Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Due Nov 22, 2028National Institutes of Health · Up to $500K
This NIH/NCI U01 cooperative agreement funds research projects within the Metastasis Research Network that use systems-level approaches to study cancer metastasis as a whole-body problem. Both U.S. and foreign organizations may apply, but applications including funded foreign subawards/subcontracts will be deemed noncompliant. The award ceiling is up to about $500,000.
ResearchersSchools & universitiesLarge awardBroad eligibilityFOUNDATIONS OF TRUSTED SYSTEMS
Due Dec 5, 2028Air Force -- Research Lab · Up to $99.9M
This is an Air Force Research Lab research-and-development opportunity (Foundations of Trusted Systems) for organizations working in defense-related science and technology. The total ceiling across the program is very large (up to roughly $99.9M), so awards typically go to established research institutions, universities, and contractors rather than small applicants. Full eligibility and requirements are only in the linked SAM.gov notice, so review that posting before applying.
ResearchersSchools & universitiesLarge awardNarrow eligibilityUpdated National Dislocated Worker Grant Program Guidance and Application Information
Due Dec 31, 2028Employment and Training Administration · $150K–$10M
This U.S. Department of Labor program provides National Dislocated Worker Grants to help communities respond to layoffs and disasters that displace workers. Eligibility is restricted to government and workforce entities such as state workforce agencies, local Workforce Development Boards, outlying areas, and Indian tribal governments, depending on the grant type; individual nonprofits and businesses are not direct applicants. Awards are large, ranging from about $150,000 up to roughly $10M.
Government / tribalLarge awardNarrow eligibilityMathematical Sciences Research Institutes
Due Mar 14, 2029U.S. National Science Foundation · $1.5M–$6.5M
This National Science Foundation program funds Mathematical Sciences Research Institutes as national resources that advance research in mathematics and statistics and broaden participation, with awards ranging roughly from $1.5 million to $6.5 million. Only U.S.-based non-profit non-academic research organizations and accredited institutions of higher education may apply; multi-institutional consortia are allowed but one entity must take overall management responsibility. Individuals and for-profit firms are not eligible.
Schools & universitiesNonprofitsResearchersLarge award+1 moreCoordinating Austere Nodes through Virtualization and Analysis of Streams (CANVAS)
Due May 22, 2029Air Force -- Research Lab · Up to $24.9M
This Air Force Research Laboratory opportunity (CANVAS) funds research on coordinating austere/edge computing nodes through virtualization and analysis of data streams, with a ceiling reported up to roughly $24.9 million. No Grants.gov submissions are accepted; all applications must follow the instructions in the linked SAM.gov announcement, which also holds the full eligibility details. Prospective applicants must review the SAM.gov notice to determine whether they qualify.
ResearchersLarge awardCausal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
Due Jul 5, 2029National Institutes of Health · Up to $500K
This NIH (U01) cooperative agreement funds research into the human behaviors that affect oral and systemic health among people with chronic conditions, including projects that develop or test causal hypotheses, with a stated budget up to about $500,000. It is aimed at research institutions studying behavioral, biological, and psychosocial drivers of health outcomes. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.
ResearchersSchools & universitiesLarge awardNarrow eligibilityNIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
Due Jul 5, 2029National Institutes of Health · Up to $500K
This NIH/NIDCR (U01) cooperative agreement funds investigator-initiated observational or biomarker validation studies that require prospective collection or continued analysis of data and biospecimens, with a stated budget up to about $500,000. It is aimed at research institutions in NIDCR (dental, oral, and craniofacial) mission areas. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.
ResearchersSchools & universitiesLarge awardNarrow eligibilityBioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
Due Jul 5, 2029National Institutes of Health · Up to $500K
This NIH (R01) Bioengineering Research Grant funds multidisciplinary projects that apply engineering approaches to biomedical, clinical, or translational problems, with a stated budget up to about $500,000. It supports clinical trials that validate performance but excludes Phase III trials, conventional non-translational trials, and commercial production. Eligibility is relatively broad for an NIH grant: both foreign organizations and foreign components of U.S. organizations are eligible to apply, though foreign components (as defined by NIH) are not allowed.
ResearchersSchools & universitiesLarge awardResearch and Development (RAD) Directed Energy (RD) University Assistance Instruments
Due Jul 18, 2029Air Force -- Research Lab · Up to $49M
This Air Force Research Laboratory funding opportunity supports university research and development in directed energy, with a program cost ceiling of roughly $49 million and a mandatory letter of intent required before full proposals. The announcement is aimed at universities (university assistance instruments), but full eligibility details are in the FOA itself, which applicants must consult. Because it is defense-focused, expect a security risk review as part of the selection process.
Schools & universitiesResearchersLarge awardNarrow eligibilityAutomated Processes for Knowledge Discovery and Information Retrieval
Due Sep 9, 2029Air Force -- Research Lab · Up to $99M
This Air Force Research Laboratory opportunity funds research in automated knowledge discovery and information retrieval, with a ceiling reported up to roughly $99 million across the program. Note that no Grants.gov submissions are accepted; all applications must follow instructions in the linked SAM.gov announcement, which also contains the full eligibility details. Because the eligibility criteria are not stated here, prospective applicants must review the SAM.gov notice to confirm whether they qualify.
ResearchersLarge awardSEEDING CRITICAL ADVANCES FOR LEADING ENERGY TECHNOLOGIES WITH UNTAPPED POTENTIAL (SCALEUP) READY
Due Sep 29, 2029Advanced Research Projects Agency Energy · $5M–$20M
ARPA-E's SCALEUP READY program funds the scale-up of promising clean and advanced energy technologies, with awards in the range of roughly $5 million to $20 million. It targets organizations developing transformative energy technologies aimed at improving U.S. energy security, efficiency, and emissions. Specific eligibility is set out in the NOFO (Section II.A.) available on the ARPA-E eXCHANGE site; applications must be submitted through that portal rather than Grants.gov, and cost-share is typical for ARPA-E awards, so review the NOFO before applying.
ResearchersSmall businessLarge awardCHIPS Research and Development Office (CRDO) Broad Agency Announcement (BAA)
Due Sep 30, 2029National Institute of Standards and Technology · From $10M
This NIST CHIPS R&D Office Broad Agency Announcement funds research, prototyping, and commercial solutions that advance U.S. microelectronics technology, with a stated floor of about $10 million per award. Eligible applicants include for-profit and non-profit organizations, accredited universities, FFRDCs, and federal entities, but they must be domestic; individuals and unincorporated sole proprietors are not eligible. Some foreign partners may participate as subawardees, subject to restrictions (foreign adversaries excluded). Given the large award size, applicants should review the full BAA for compliance requirements.
Small businessNonprofitsSchools & universitiesResearchers+3 moreAir Dominance Broad Agency Announcement (BAA)
Due Oct 31, 2029Munitions Directorate · Up to $750M
This Air Force (Munitions Directorate) Broad Agency Announcement funds research and development supporting air dominance, with a program ceiling reported up to roughly $750 million. Eligibility is described as unrestricted and open to any type of entity, subject to any clarifications in the full announcement, making it broadly accessible to businesses, universities, and nonprofits. Because it is defense-focused R&D, applicants should expect security and compliance requirements and should review the full BAA for specifics.
ResearchersSmall businessNonprofitsSchools & universities+3 more