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Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)

National Institutes of HealthAmount not specifiedDue Oct 11, 2026
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This NIH R01 supports research institutions and investigators studying how to design rigorous clinical trials of rapid-acting psychotropic drugs (RAPIDs) and adjunctive psychosocial interventions. …

Deadline
Oct 11, 2026
Posted
Apr 29, 2026
Award amount
Amount not specified
Focus areas
Health

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We’ll email you before Oct 11, 2026 so you have time to apply.

In plain English

This NIH R01 supports research institutions and investigators studying how to design rigorous clinical trials of rapid-acting psychotropic drugs (RAPIDs) and adjunctive psychosocial interventions. A clinical trial is required, so applicants must be prepared to run one. Foreign (non-U.S.) organizations, foreign components of U.S. organizations, and foreign components generally are not eligible or allowed. The notice does not state an award ceiling; refer to the NOFO for eligibility and budget details.

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Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

About this grant

The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-acting psychotropic interventional drugs (RAPIDs) by addressing the methodological challenges involved with these clinical trials. In addition, this NOFO seeks to advance understanding of how RAPIDs and adjunctive psychosocial interventions can be optimally delivered, monitored, and sustained over time to enhance effectiveness and generalizability. The NOFO will support studies designed to enhance the rigor of RAPID clinical trial design, which will ultimately increase the interpretability of the data and the generalizability of the results.

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