Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
An NIH/NIMH research project grant (R01, clinical trial required) funding effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions across the l…
- Deadline
- Jan 7, 2028
- Posted
- Oct 31, 2024
- Award amount
- Amount not specified
- Focus areas
- Health
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We’ll email you before Jan 7, 2028 so you have time to apply.
In plain English
An NIH/NIMH research project grant (R01, clinical trial required) funding effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions across the lifespan. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and faith- or community-based organizations. No specific award ceiling is stated. This requires conducting a clinical trial, so it suits research institutions with that capacity rather than individuals or general nonprofits.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
About this grant
NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting youth, adults, and older adults. This Notice of Funding Opportunity (NOFO) encourages clinical trials to establish the effectiveness and test hypotheses regarding moderators, mediators, and mechanisms of action of post-acute phase therapeutic and services interventions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden for promoting optimal longer-term outcomes. This NOFO is intended to support effectiveness trials testing post-acute phase interventions that are statistically powered to provide a definitive answer regarding the study intervention's effectiveness. Support for pilot effectiveness trials to evaluate the initial feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches is provided via a companion R34 (Currently TEMP-24814)
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