Health Grants for Governments & tribes

National Institutes of Health · Up to $500K

This NIH/National Cancer Institute R01 funds investigator-initiated early-phase (Phase 0, I, II) clinical trials for cancer diagnosis and treatment; a clinical trial is required. Eligible applicants include universities, research institutions, hospitals, tribal and community organizations, and foreign organizations. The maximum award is just under $500,000. It is geared toward established clinical research teams.

National Institutes of Health · Amount varies

This NIH R01 funds preclinical and patient-based research into how incretin mimetics (such as GLP-1 agents) affect cancer risk. Eligible applicants include universities, research institutions, tribal and community organizations, and foreign organizations; a clinical trial is optional. It requires established research capacity in this area. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH R21 funds preclinical and patient-based research into how incretin mimetics (such as GLP-1 agents) affect cancer risk; no clinical trial is allowed. Eligible applicants include universities, research institutions, tribal and community organizations, and foreign organizations. It requires research capacity in this area. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH R01 supports research on improving access to and quality of evidence-based practices for youth mental health, including in rural, urban, and under-resourced settings. Eligible applicants include universities, research institutions, and tribal and community organizations, but foreign (non-U.S.) organizations are not eligible to apply and foreign components are not allowed. A clinical trial is optional. It is aimed at research teams with mental-health services research expertise. No specific award amount is stated.

National Institutes of Health · Up to $500K

This NIH/National Cancer Institute R01 funds academic-industrial partnerships to translate and validate in vivo imaging, data science, or spectroscopic technologies into tools for cancer and other diseases; a clinical trial is optional. Eligible applicants include universities, research institutions, and tribal and community organizations, and foreign organizations are listed among eligible applicants. The award maximum is about $500,000, and the model assumes an academic-industry collaboration. It is aimed at research teams.

National Institutes of Health · Amount varies

This NIH/NHLBI R34 funds pilot studies that inform the planning of larger Phase II-IV clinical trials for heart, lung, blood, and sleep disorders; a clinical trial is optional. Eligible applicants include universities, research institutions, and tribal and community organizations; foreign organizations are not eligible to apply, though non-U.S. components of U.S. organizations are. It is a planning mechanism for research teams preparing larger trials. No specific award amount is stated.

Office of the Assistant Secretary for Health · $200K–$22M

This Title X program funds voluntary family planning services across U.S. states and territories. Eligible applicants are broad and include state, local, and tribal governments, public and private institutions of higher education, public housing authorities, and nonprofits with or without 501(c)(3) status. Awards are large, with individual amounts running into the millions and roughly $257 million expected across about 90 awards. The work must deliver clinical family planning services to low-income and uninsured populations, so applicants generally need health-service delivery capacity.

National Institutes of Health · Up to $350K

This NIH HEAL Initiative R61/R33 funds early translational drug-discovery research toward non-addictive pain therapeutics, including assay development, screening, and initial characterization of candidate agents; no clinical trial is allowed. Eligible applicants include universities, research institutions, and tribal and community organizations, but foreign organizations are not eligible to apply. The maximum award is about $350,000. It requires drug-discovery research capacity.

National Institutes of Health · Amount varies

An NIH UE5/T32 award that funds federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to build graduate-level research training in AI/AN health. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible. No award amount is specified. This is a narrow opportunity limited to Tribal applicants and is not a fit for other nonprofits, small businesses, or individuals.

Department of Housing and Urban Development · $112.5K–$250K

A HUD program providing one-time, cost-reimbursable grants for service coordination and limited direct services to residents of HUD-assisted housing facing emergencies such as natural disasters or public-health crises. Eligible applicants include public/Indian housing authorities, nonprofits (with or without 501(c)(3) status, including resident associations), multifamily owners, Tribal governments and entities, and faith-based organizations, so eligibility is relatively broad among housing-connected organizations. Awards run roughly $112,500 to $250,000. Note that funds are reimbursed after costs are incurred and serve HUD-assisted housing residents specifically.

National Institutes of Health · Amount varies

An NIH UE5/T34 award funding federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to develop undergraduate-level research training in AI/AN health. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible. No award amount is specified. Like its T32 counterpart, this is narrow and not a fit for non-Tribal nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R24 funding federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to establish or strengthen Tribal Institutional Review Boards. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible, and clinical trials are not allowed. No award amount is specified. This is narrow and not a fit for non-Tribal nonprofits, small businesses, or individuals.

Centers for Disease Control - OPHPR · $50K–$5M

A CDC cooperative agreement that pre-positions states, large local governments, and federally recognized Tribes on an approved-but-unfunded roster for rapid public-health emergency response. Eligibility is limited to government public-health entities, with population thresholds (e.g., counties of 2 million or more, cities of 400,000 or more, Tribes serving 50,000 or more), so it is restricted to large jurisdictions. Listed award range is about $50,000 to $5,000,000, but funding is only released if a public health emergency is declared. Not a fit for nonprofits, small businesses, individuals, or smaller jurisdictions.

National Institutes of Health · Amount varies

This NIH (R61/R33) phased opportunity funds mechanistic research to advance precision probiotic therapies, beginning with an exploratory phase to identify person-specific factors and a second phase to test them in animal models or human subjects, over a combined period of up to five years. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Transition between phases depends on meeting milestones. It is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH (R33) opportunity funds mechanistic research to advance precision probiotic therapies by characterizing person-specific factors that affect probiotic responses, using animal models or human subjects. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It expects supportive preliminary data and is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative (U01) program funds development of next-generation sensors and bioelectronic devices that synchronize with brain recordings to build computational models of human and animal behavior. Eligible applicants are research organizations including universities, colleges, government and tribal entities, and faith- or community-based organizations; it targets established research and technology-development teams, not individuals or general nonprofits. Award amounts are not specified. Confirm program-specific eligibility in the full announcement.

National Institutes of Health · Amount varies

This NIH (NIDCD, R21) opportunity is a planned re-issue to support early-stage dissemination and implementation research in hearing, balance, taste, smell, voice, speech, and language. For this announcement foreign organizations and non-U.S. components are eligible to apply, but NIH will not issue awards involving foreign subawards/subcontracts unless submitted under a specifically designated international-collaboration announcement. Note the announcement states applications are not being solicited at this time, so it is a notice of intent rather than an open call. It is intended for research institutions, not individuals or general nonprofits. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH (R21) opportunity funds preclinical efficacy studies in established rare-disease models to demonstrate that a candidate therapeutic warrants further development, including supporting pharmacokinetic and pharmacodynamic studies. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It is intended for research teams advancing therapeutic candidates, not individuals or general nonprofits. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.