Grants for State, Local & Tribal Governments

U.S. National Science Foundation · $1M–$1.5M

An NSF EPSCoR program funding interjurisdictional research collaborations in STEM, open to higher-education institutions, certain nonprofit research organizations with 501(c)(3) status, and Tribal governments located in EPSCoR-eligible jurisdictions. Applicants and investigators must be in EPSCoR jurisdictions and projects must span at least two such jurisdictions, which is a significant geographic restriction. Awards run roughly $1,000,000 to $1,500,000. Not a fit for organizations outside EPSCoR-eligible jurisdictions or without a research mission.

National Institutes of Health · Amount varies

An NIH R24 funding federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to establish or strengthen Tribal Institutional Review Boards. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible, and clinical trials are not allowed. No award amount is specified. This is narrow and not a fit for non-Tribal nonprofits, small businesses, or individuals.

Department of Parks and Recreation · $1K–$10K

This California grant is open only to public agencies (cities, counties, districts) that previously received Boating and Waterways funding for a project — it is not for nonprofits, businesses, or individuals. It pays for installing or replacing signs that are obsolete, damaged, missing, or needed for safety at those existing facilities, with awards ranging from about $1,000 to $10,000. Applications are due February 1, 2027.

Department of Parks and Recreation · Amount varies

Open only to public agencies in California (not nonprofits, businesses, or individuals), this program funds the creation or improvement of public non-motorized boat launching access, such as small hand-launched boat ramps, parking lots, and restrooms. No award amount is listed in this record, so applicants should confirm funding levels with the funder. Applications are due February 1, 2027.

Department of Parks and Recreation · Amount varies

This California grant is restricted to local government agencies and funds construction or improvement of boat launching facilities — ramps, restrooms, boarding floats, shore protection, and vehicle/trailer parking — plus related engineering, permitting, and inspection costs. It is not open to nonprofits, businesses, or individuals, and no award amount is specified in this record. Applications are due February 1, 2027.

Department of Parks and Recreation · Amount varies

This California program is limited to public agencies that operate DBW-funded boat launching facilities and covers repairs or ramp extensions needed after flood, wildfire, accident damage, or drought-related low water levels. It is not open to nonprofits, businesses, or individuals, and no award amount is specified in this record. Applications are due February 1, 2027.

Council on the Arts · Up to $25K

Creative Catalyst is a Pennsylvania Council on the Arts program funding new initiatives that support creative workers and industries around asset development, workforce, community development, visibility, or policy. It's open to nonprofits, municipalities, school districts, and other non-arts nonprofits that provide arts programming or services, provided the project has statewide or broad regional reach. Awards go up to $25,000.

Centers for Disease Control - OPHPR · $50K–$5M

A CDC cooperative agreement that pre-positions states, large local governments, and federally recognized Tribes on an approved-but-unfunded roster for rapid public-health emergency response. Eligibility is limited to government public-health entities, with population thresholds (e.g., counties of 2 million or more, cities of 400,000 or more, Tribes serving 50,000 or more), so it is restricted to large jurisdictions. Listed award range is about $50,000 to $5,000,000, but funding is only released if a public health emergency is declared. Not a fit for nonprofits, small businesses, individuals, or smaller jurisdictions.

Department of Housing and Community Development · Amount varies

This California housing program funds predevelopment, construction, rehabilitation, and preservation of affordable rental and ownership housing, plus homelessness services like rapid rehousing and shelter operations. It's restricted to public agencies — cities, counties, and other government entities — so nonprofits, businesses, and individuals can't apply directly. No award amount is specified.

Department of Housing and Community Development · Amount varies

This California housing program funds predevelopment, construction, rehabilitation, and preservation of affordable rental and ownership housing, plus homelessness services like rapid rehousing and shelter operations. It's restricted to public agencies — cities, counties, and other government entities — so nonprofits, businesses, and individuals can't apply directly. No award amount is specified.

Environmental Protection · Up to $35K

This Illinois EPA grant (FY27) reimburses units of local government up to $35,000 for costs of running a residential sharps (needle) collection program, including advertising, educational materials, collection containers, and disposal fees. Only local government units that are pre-qualified through the state's GATA Grantee Portal with an approved Internal Control Questionnaire are eligible; nonprofits and businesses cannot apply, and only residential (not business) sharps waste is covered. The deadline is March 1, 2027.

U.S. National Science Foundation · $100K–$750K

An NSF program funding research on the coupling, energetics, and dynamics of the upper atmosphere, including ground- and space-based observations and modeling. Eligibility is relatively broad: U.S. for-profit organizations including small businesses, nonprofit non-academic research organizations, higher-education institutions, and federally recognized Tribal Nations may apply. Awards run roughly $100,000 to $750,000. While the entity types are broad, the work is specialized atmospheric science suited to research-capable applicants.

U.S. National Science Foundation · $300K–$1M

An NSF program funding development and testing of innovative approaches to STEM graduate education. Eligible applicants are U.S. two- and four-year higher-education institutions (including community colleges), certain nonprofit non-academic research/education organizations, and federally recognized Tribal Nations. Awards run roughly $300,000 to $1,000,000. This is geared to colleges, universities, and education-focused nonprofits rather than small businesses or individuals.

Dept of the Army -- Materiel Command · Amount varies

A U.S. Army (West Point / U.S. Military Academy) Broad Agency Announcement soliciting basic and applied research and analysis across science, engineering, education, policy, ethics, history, and economics. Eligibility is broad, including higher-education institutions, nonprofits, state and local governments, for-profit organizations (large and small businesses), and foreign organizations/public entities, with no restriction on place of performance. No award amount is specified, and funding depends on the specific proposal. Proposals must advance the state of the art or basic knowledge rather than target specific devices.

Food and Drug Administration · Up to $200K

This FDA cooperative agreement funds state and academic partners to strengthen antibiotic-resistance surveillance in retail food specimens as part of the NARMS program. Eligibility is broad, spanning universities, nonprofits (with or without 501(c)(3) status), small and large businesses, and state, local, and tribal governments. Awards range up to $200,000.

Food and Drug Administration · Up to $300K

This FDA cooperative agreement funds state animal food safety programs working toward or maintaining full implementation of national inspection standards, with optional add-ons for mutual-reliance partnerships. It's restricted to state programs that already hold an active FDA inspectional contract and a valid prior agreement — a narrow, technical bar that rules out most nonprofits and businesses. Awards go up to $300,000 depending on funding track and tier.

U.S. National Science Foundation · Amount varies

This NSF program funds open-science work such as research data management, cyberinfrastructure, and scientific publication models that make research data findable, accessible, interoperable, and reusable. Eligibility is limited to U.S. institutions of higher education, non-profit non-academic research organizations, federally recognized tribal nations, and certain federal agencies and FFRDCs. No award amount is listed.

U.S. National Science Foundation · Amount varies

This NSF solicitation funds Antarctic research that requires logistical fieldwork support from the U.S. Antarctic Program (USAP), spanning Earth systems, biological, geochemical, and physical sciences. Eligible applicants are limited to U.S.-based non-profit non-academic research organizations (such as museums, observatories, and research laboratories), accredited U.S. institutions of higher education, and federally recognized tribal nations; individuals and businesses are not among the listed eligible submitters. Available USAP logistical support is currently limited due to facility maintenance, so applicants should follow the solicitation's guidance. Award amounts are not specified.

AGRICULTURE & MARKETS · Up to $67M

This New York State Round 20 Farmland Protection Implementation Grant funds governmental entities and not-for-profit organizations to help cover the cost of establishing perpetual agricultural conservation easements on farmland at risk of conversion to non-farm uses, with awards up to $67,000,000. Projects must align with an adopted county or municipal agricultural and farmland protection plan. The deadline is June 1, 2027.

National Institutes of Health · Amount varies

This NIH (R61/R33) phased opportunity funds mechanistic research to advance precision probiotic therapies, beginning with an exploratory phase to identify person-specific factors and a second phase to test them in animal models or human subjects, over a combined period of up to five years. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Transition between phases depends on meeting milestones. It is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.