NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
This NIH NOFO funds multi-center clinical trials for neurological emergencies conducted within the NIH SIREN Network; a clinical trial is required. A broad set of applicants is eligible, including …
- Deadline
- Jul 9, 2026
- Posted
- Nov 7, 2024
- Award amount
- Amount not specified
- Focus areas
- Health
In plain English
This NIH NOFO funds multi-center clinical trials for neurological emergencies conducted within the NIH SIREN Network; a clinical trial is required. A broad set of applicants is eligible, including higher-education institutions, minority-serving institutions, HBCUs, tribal governments and organizations, faith- and community-based organizations, regional organizations, federal agencies, U.S. territories, and foreign organizations. Applicants need not already be part of the SIREN infrastructure. Award amounts are not stated; see the NOFO for details.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
About this grant
This announcement (NOFO) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.
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