Oral Diseases and Disorders Research Grants (Assistance Listing 93.121)
Administered by National Institutes of Health. An Assistance Listing is the permanent catalog entry for a federal funding program — individual opportunities are issued under it and come and go.
Overview
Assistance Listing 93.121 — Oral Diseases and Disorders Research — is a federal funding program administered by National Institutes of Health. UseGrants has tracked 92 funding opportunities issued under it, of which 78 are accepting applications right now. A further 7 are forecast — announced by the agency but not yet open. The typical award ceiling is $350,000, with the largest at $4,000,000. Historically, opportunities under this listing post most often in June and May.
Eligibility is set per opportunity, not per listing. The free UseGrants check matches your organization type and focus against every open opportunity, including these.
- Open now
- 78
- Forecast
- 7
- Opportunities tracked
- 92
- Typical ceiling
- $350K
- Largest ceiling
- $4M
- Assistance Listing
- 93.121
Open opportunities under 93.121
78 opportunities are accepting applications, newest first. Confirm every detail on the issuing agency’s official listing before you apply.
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
Due Jul 5, 2029National Institutes of Health · Up to $500K
This NIH/NIDCR (U01) cooperative agreement funds investigator-initiated observational or biomarker validation studies that require prospective collection or continued analysis of data and biospecimens, with a stated budget up to about $500,000. It is aimed at research institutions in NIDCR (dental, oral, and craniofacial) mission areas. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.
ResearchersSchools & universitiesLarge awardNarrow eligibilityPredoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
Due Apr 8, 2029National Institutes of Health · Amount varies
This NIH Predoctoral-to-Postdoctoral Transition Award (F99/K00) supports promising graduate students as they finish doctoral research and move into mentored postdoctoral career development, in NIH mission-relevant fields. It is a mentored training award administered through institutions; candidates may not lead an independent clinical trial but may participate in a sponsor-led one. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.
Schools & universitiesResearchersNarrow eligibilityNIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)
Due May 5, 2029National Institutes of Health · Amount varies
This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.
Schools & universitiesResearchersNarrow eligibilityNIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed)
Due May 5, 2029National Institutes of Health · Amount varies
This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.
Schools & universitiesResearchersNarrow eligibilityNIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed)
Due May 25, 2029National Institutes of Health · Amount varies
This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.
Schools & universitiesResearchersNarrow eligibilityCausal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
Due Jul 5, 2029National Institutes of Health · Up to $500K
This NIH (U01) cooperative agreement funds research into the human behaviors that affect oral and systemic health among people with chronic conditions, including projects that develop or test causal hypotheses, with a stated budget up to about $500,000. It is aimed at research institutions studying behavioral, biological, and psychosocial drivers of health outcomes. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.
ResearchersSchools & universitiesLarge awardNarrow eligibilityNIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
Due Apr 5, 2027National Institutes of Health · Amount varies
This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.
Small businessNarrow eligibilityMaximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)
Due Dec 2, 2026National Institutes of Health · Amount varies
NIH individual postdoctoral fellowship (F32) supporting a named postdoctoral fellow to analyze the ECHO program's longitudinal child-health dataset within the NICHD DASH repository. This is an individual fellowship awarded through a sponsoring US institution; foreign organizations are not eligible and foreign components are not allowed. No award amount is stated. It is restricted to eligible postdoctoral researchers at a US institution, so eligibility is narrow.
ResearchersIndividualsSchools & universitiesNarrow eligibilitySBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
Due Apr 5, 2029National Institutes of Health · Amount varies
This NIH SBIR/STTR Commercialization Readiness Pilot (CRP) is restricted to U.S. small business concerns (as defined by the SBA) and helps move NIH-funded SBIR/STTR projects from late-stage development toward commercialization. It supports later-stage R&D and technical assistance such as replication studies, IND/IDE-enabling work, clinical studies, manufacturing scale-up, and regulatory support, and a significant portion may be subcontracted. Foreign organizations are not eligible to apply.
Small businessNarrow eligibilityNIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
Due Apr 5, 2027National Institutes of Health · Amount varies
This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.
Small businessNarrow eligibilityLimited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
Due Jan 26, 2029National Institutes of Health · $25K–$250K
This NIH S10 instrumentation grant funds resource-limited institutions to purchase state-of-the-art scientific instruments supporting biomedical research and education. It is a limited competition that invites applications only from eligible organizations, and awards range from about $25,000 to $250,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.
Schools & universitiesResearchersNarrow eligibilityAcademic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)
Due Jul 12, 2029National Institutes of Health · Amount varies
This NIH career development award (K32) supports up to three years of mentored research and career development for early-stage postdoctoral scholars, with applications submitted around the start of the postdoctoral position. It is an institutional/mentored mechanism aimed at developing future independent investigators, so it suits universities and research institutions. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.
Schools & universitiesResearchersNarrow eligibilityHEAL INITIATIVE: INTERACT Data Coordination and Integration Center (U24 Clinical Trial Not Allowed)
Due Oct 1, 2026National Institutes of Health · Amount varies
This NIH HEAL Initiative U24 cooperative agreement funds a Data Coordination and Integration Center to manage and integrate pain-associated data from the INTERACT program and related musculoskeletal datasets. Foreign organizations and foreign components are not eligible to apply; refer to the NOFO's eligibility section for the full list of eligible domestic applicants. Clinical trials are not allowed under this mechanism. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityINCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
Due Jun 15, 2028National Institutes of Health · Up to $500K
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreINCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
Due Jun 15, 2028National Institutes of Health · Up to $200K
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R21 funds exploratory, higher-risk Down syndrome research — feasibility studies, novel methods, or new applications of existing techniques. Awards up to about $200,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribalNIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)
Due May 25, 2029National Institutes of Health · Amount varies
The NIH Science Education Partnership Award (SEPA, R25) funds educational projects that increase understanding of biomedical research among pre-college (pre-K through grade 12) students and encourage interest in STEM careers. It suits universities, research institutions, and education-focused organizations that can run science education programs. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.
Schools & universitiesNonprofitsNarrow eligibilityCommunity Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)
Due Oct 19, 2026National Institutes of Health · Amount varies
This NIH U01 cooperative agreement funds a single Community Engagement Evaluation and Data coordination (CEED) hub to support a community-based participatory research consortium focused on oral health, coordinating data planning, community engagement evaluation, and operational support. Clinical trials are not allowed, and as a cooperative agreement NIH staff are substantially involved. This is a narrow, single-hub coordination role rather than a broad research grant. Foreign organizations, the foreign components of U.S. organizations, and foreign components are not eligible or allowed; see the NOFO for full eligibility details. No award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityCommunity-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)
Due Nov 16, 2028National Institutes of Health · Up to $300K
This NIH UG3/UH3 cooperative agreement funds community-based participatory research that tests population-level interventions to improve oral health by addressing social and chronic-disease risk factors through cross-sector community partnerships. The award ceiling is up to about $300,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, and foreign components are not allowed.
ResearchersSchools & universitiesNonprofitsNarrow eligibilityAdministrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Due Nov 30, 2028National Institutes of Health · Amount varies
This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.
ResearchersSchools & universitiesNarrow eligibilityStephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
Due Aug 25, 2028National Institutes of Health · Amount varies
Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.
ResearchersSchools & universitiesNonprofitsGovernment / tribalExpanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
Due Feb 17, 2028National Institutes of Health · Amount varies
Open to U.S. universities, research institutions, nonprofits, and certain government and tribal organizations; foreign organizations are not eligible. This NIH R21 funds exploratory, early-stage projects developing methods or agents to target 'undruggable' molecules in serious diseases. Award size isn't specified and follows standard NIH R21 limits; best suited to researchers pursuing high-risk, innovative therapeutics.
ResearchersSchools & universitiesNonprofitsGovernment / tribalNIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH award funds dual-degree dentist scientists (e.g., DDS/PhD) transitioning from mentored postdoctoral training into independent, tenure-track research careers focused on dental, oral, and craniofacial health. It is narrowly limited to individuals in this specific clinical-research career path; foreign organizations and their non-U.S. components are not eligible. No award amount is specified, and the deadline is not imminent.
ResearchersIndividualsNarrow eligibilityBlueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)
Due Jan 28, 2028National Institutes of Health · Amount varies
This NIH program (Blueprint MedTech Translator) funds translational research and clinical feasibility studies for therapeutic and diagnostic devices targeting nervous- or neuromuscular-system disorders, open to a broad range of institutions including HBCUs, Hispanic-serving institutions, tribal colleges, faith- and community-based organizations, and individuals or businesses developing their own devices. It is a milestone-driven cooperative agreement requiring NIH staff involvement in project planning and monitoring. No award amount is specified, and the deadline is not imminent.
NonprofitsSmall businessResearchersSchools & universities+1 moreSupport for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
Due Sep 7, 2028National Institutes of Health · Up to $100K
This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.
Schools & universitiesResearchersSmall awardNarrow eligibilitySupport for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
Due Sep 7, 2028National Institutes of Health · Up to $125K
This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.
Schools & universitiesResearchersSmall awardNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.
ResearchersIndividualsNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH fellowship supports experienced individual scientists who want to redirect their research careers or gain new independent research skills in fields relevant to NIH's mission. It is an individual fellowship (awarded via a sponsoring institution), not a project grant for organizations, and eligibility text names foreign organizations as an other-eligible applicant category, which is unusual for NIH. No specific award amount is listed, and the deadline is set years out (2028), so there is no urgency to apply.
ResearchersIndividualsNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.
ResearchersIndividualsNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH fellowship supports predoctoral students in combined MD/PhD or similar dual-doctoral degree programs at institutions that already have an NIH-funded dual-degree training program, preparing them for physician-scientist careers. It is limited to individual student applicants; foreign organizations and their non-U.S. components are not eligible, and applicants may not lead an independent clinical trial. No award amount is listed, and the deadline is not imminent.
ResearchersIndividualsNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
Due May 7, 2028National Institutes of Health · Amount varies
This NIH fellowship funds individual predoctoral students conducting dissertation research in health-related fields under a faculty sponsor, with the goal of developing them into independent researchers. It is limited to individual applicants (not organizations); foreign organizations are named as an other-eligible category, and applicants may not lead an independent clinical trial. No specific award amount is listed, and the deadline is several years out.
ResearchersIndividualsNarrow eligibilityShort Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
Due Apr 9, 2027National Institutes of Health · Up to $200K
This NIH R25 supports short courses that teach innovative research methods in the behavioral and social sciences, aimed at developing the biomedical research workforce. Eligible applicants are research institutions such as universities and minority- or tribal-serving colleges, with foreign organizations excluded. Awards go up to $200,000.
ResearchersSchools & universitiesIntervention Research to Improve Native American Health (R01 Clinical Trial Optional)
Due Jan 7, 2027National Institutes of Health · Amount varies
This NIH R01 funds larger-scale research testing and disseminating interventions to improve health in Native American populations, following the same research focus as its companion R34 announcement. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with foreign entities restricted. No award amount is specified.
ResearchersBroad eligibilityIntervention Research to Improve Native American Health (R34 Clinical Trial Optional)
Due Jan 7, 2027National Institutes of Health · Amount varies
This NIH R34 funds early-stage research and pilot studies testing interventions to improve health outcomes in Native American communities, including etiologic research and culturally-informed treatment studies. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with some restrictions on foreign entities. No award amount is specified; a clinical trial component is optional.
ResearchersBroad eligibilityEthical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
Due Nov 16, 2026National Institutes of Health · Up to $50K
This NIH grant (up to $50,000) funds small research projects studying the ethical, legal, and social implications (ELSI) of human genetics and genomics, including single-investigator studies, preliminary data collection, and secondary data analysis. It's aimed at eligible U.S. and territorial research institutions. The deadline is November 16, 2026.
ResearchersSmall awardNarrow eligibilityEthical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
Due Nov 18, 2026National Institutes of Health · Amount varies
This NIH R21 grant funds exploratory and developmental research into the ethical, legal, and social implications of human genetics and genomics, particularly studies examining new or emerging genomic technologies. It's open to eligible U.S. and territorial research institutions using empirical, conceptual, legal, or normative methods. The deadline is November 18, 2026.
ResearchersSchools & universitiesNarrow eligibilityHEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
Due Nov 23, 2026National Institutes of Health · Up to $375K
NIH HEAL Initiative R15 funding for basic or mechanistic pain research at institutions eligible for the R15 (Research Enhancement) mechanism, which targets schools and components that have not been major NIH recipients. Aimed at engaging undergraduate, graduate, and health-professional trainees in the research; foreign organizations are not eligible. The listed maximum is about $375,000. R15 eligibility rules restrict which institutions can apply, so eligibility is narrow.
ResearchersSchools & universitiesNarrow eligibilityAcademic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Up to $499K
An NIH/NCI research project grant (R01, clinical trial not allowed) funding academic-industrial partnerships to translate scientific and engineering advances into tools for disease risk assessment, detection, diagnosis, and treatment. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $499,000. The partnership focus suits research institutions collaborating with industry rather than individuals.
ResearchersSchools & universitiesGovernment / tribalNonprofits+2 moreNIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreNIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreLimited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
Due Oct 19, 2027National Institutes of Health · Up to $650K
This NIH limited-competition award (UG3/UH3) funds collaborative innovation projects within the CTSA Program consortium to accelerate translational research. Eligibility is restricted per the funding notice, and foreign organizations and their U.S. components are not eligible, so this is aimed at institutions already in or aligned with the CTSA consortium rather than the general public. Awards run up to roughly $650,000. Review the notice's eligibility section closely, as access is limited.
ResearchersSchools & universitiesLarge awardNarrow eligibilityExploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
An NIH/NCI exploratory/developmental bioengineering research grant (EBRG, R21, clinical trial not allowed) funding feasibility-stage projects that develop new capabilities or improvements for biomedical, pre-clinical, or clinical research and care. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a bioengineering research mechanism aimed at research institutions.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreResearch Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Up to $375K
The REAP program funds small-scale research at health professional and graduate schools that haven't been major recipients of NIH support, while giving students hands-on research experience. Eligibility is limited to institutions awarding NIH-relevant degrees that received under $6 million per year in NIH support in 4 of the last 7 years — a specific financial threshold worth checking before applying. Awards go up to $375,000.
ResearchersSchools & universitiesNarrow eligibilityAcademic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Up to $375K
An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.
ResearchersSchools & universitiesNarrow eligibilityNIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Up to $500K
This NIDCR (UG3/UH3) cooperative agreement funds planning and implementation of behavioral and social intervention clinical trials for dental, oral, or craniofacial conditions, with a milestone-driven planning phase before transition to a full trial. A clinical trial is required. It is aimed at research and academic institutions; foreign organizations are not eligible. The maximum award is about $500,000.
ResearchersSchools & universitiesLarge awardNarrow eligibilityScreening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH R01 funds studies testing innovative screening, brief intervention, and referral-to-treatment (SBIRT/P) approaches for alcohol, tobacco, and drug use in adult populations facing health disparities. Applicants should be research institutions collaborating with healthcare and community partners; eligible entities include universities, minority-serving institutions, and community organizations. No award amount is specified, and a clinical trial component is required.
ResearchersBroad eligibilitySecondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Due Nov 17, 2026National Institutes of Health · Up to $200K
NIH (NCI) R21 funding for secondary analysis and integration of existing datasets to study cancer risk and related outcomes; clinical trials are not allowed under this notice. Intended for research institutions and investigators, including minority-serving and tribal colleges. The listed maximum is about $200,000. This is institution-based research funding using existing data, not suited to individuals or general nonprofits.
ResearchersSchools & universitiesNarrow eligibilitySecondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Due Nov 6, 2026National Institutes of Health · Up to $350K
This NIH/NCI R01 grant funds secondary analysis and integration of existing datasets to study cancer risk and related outcomes such as survival and treatment response. It is a research grant for universities, research institutions, and similar eligible organizations, including various minority-serving institutions, tribal entities, and foreign organizations. The award maximum is about $350,000. Eligibility is oriented toward research institutions rather than nonprofits, small businesses, or individuals broadly, and applicants typically need access to relevant existing data.
ResearchersSchools & universitiesGovernment / tribalNIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIDCR (R03) small-grant program supports pilot or feasibility studies in oral, dental, and craniofacial research by scientists early in establishing an independent research career. It is intended for new-investigator researchers at eligible institutions; foreign organizations are not eligible to apply. No specific award amount is stated, though R03 awards are typically modest.
ResearchersSchools & universitiesNew orgs OKNarrow eligibilityRuth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
Due May 4, 2028National Institutes of Health · Amount varies
This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.
Schools & universitiesBroad eligibilityNIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIDCR (K22) career-transition award helps qualified dentists move from NIH intramural postdoctoral positions to extramural faculty roles, funding mentored training plus independent research. It is an individual career-development award for early-career dentist-scientists at eligible institutions; foreign organizations are not eligible. This is narrowly targeted and not suited to organizations seeking project funding. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityDissemination and Implementation Research in Health (R21 Clinical Trial Optional)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIH R21 funds exploratory research on dissemination and implementation strategies for evidence-based health interventions, including studies on de-implementing low-value practices. Eligible applicants include universities and similar research institutions across NIH's mission areas. No award amount is specified.
ResearchersBroad eligibilityEnhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
Due Jun 2, 2027National Institutes of Health · Amount varies
This NIH (R61/R33) phased opportunity funds mechanistic research to advance precision probiotic therapies, beginning with an exploratory phase to identify person-specific factors and a second phase to test them in animal models or human subjects, over a combined period of up to five years. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Transition between phases depends on meeting milestones. It is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityEnhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
Due Jun 2, 2027National Institutes of Health · Amount varies
This NIH (R33) opportunity funds mechanistic research to advance precision probiotic therapies by characterizing person-specific factors that affect probiotic responses, using animal models or human subjects. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It expects supportive preliminary data and is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityScreening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
An NIH research project grant (R01, clinical trial not allowed) supporting screening and functional validation of genomic variants linked to human congenital anomalies, developmental disabilities, and inborn errors of metabolism. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science genomics mechanism for research institutions.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreBiomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
Due Jan 27, 2027National Institutes of Health · Up to $500K
An NIH UC2 program helping resource-limited organizations build biomedical research capacity and sponsored-programs administration. Eligible applicants include minority-serving and Tribal colleges and other domestic organizations with limited research resources; foreign organizations are not eligible. Awards reach up to about $500,000. This targets emerging or under-resourced research institutions rather than general nonprofits, small businesses, or individuals.
Schools & universitiesResearchersLarge awardNew orgs OK+1 moreDissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIH R03 provides smaller, shorter-term funding for research on dissemination and implementation strategies — helping evidence-based health practices get adopted and sustained, or ineffective ones phased out. Eligible applicants include universities and similar research institutions across NIH's mission areas. No award amount is specified, though R03 awards are typically modest.
ResearchersBroad eligibilityDissemination and Implementation Research in Health (R01 Clinical Trial Optional)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIH R01 funds research identifying and testing strategies to help evidence-based health interventions get adopted, scaled, and sustained — or, conversely, to phase out ineffective practices. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations across NIH's mission areas. No award amount is specified.
ResearchersBroad eligibilityPilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
Due Nov 16, 2027National Institutes of Health · Up to $100K
This NIH (R03) opportunity funds pilot projects generating preliminary data on a defined list of understudied proteins associated with rare diseases. It is intended for research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $100,000.
ResearchersSchools & universitiesSmall awardNarrow eligibilityNIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Amount varies
This NIDCR (UG3/UH3) cooperative agreement funds planning and implementation of drug, biologic, device, or procedure intervention clinical trials within NIDCR's mission. A clinical trial is required. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityEmerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
Due Dec 3, 2026National Institutes of Health · Amount varies
This NIH/Fogarty K43 career development award supports an early-career scientist at an academic or research institution in a low- or middle-income country, for research that does not involve leading an independent clinical trial. Eligibility is narrow and country-restricted: only foreign institutions in qualifying LMICs may apply, U.S. organizations and their foreign components are not eligible, and some upper-middle-income G20 countries are excluded. This is not available to U.S. applicants. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityContinuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Amount varies
This NIDCR (UH3) opportunity funds competing renewal or competitive revision of ongoing clinical trials already supported by NIDCR; a clinical trial is required. Because it continues existing NIDCR-funded trials, it is effectively limited to current grantees and not open to new projects. It is aimed at research and academic institutions; foreign organizations are not eligible. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityInterventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)
Due Jan 7, 2027National Institutes of Health · Amount varies
This NIH R01 funds research testing interventions that expand cancer screening and preventive-service uptake in populations facing health disparities, ideally involving community partners. Eligible applicants include universities, minority- and tribal-serving institutions, and community-based organizations, but non-U.S. organizations and their foreign components are excluded. No award amount is specified; this is a research grant requiring a clinical trial component.
ResearchersBroad eligibilityBlueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Due Aug 18, 2027National Institutes of Health · Amount varies
This NIH program supports preclinical discovery and development of biologic-based therapies for nervous system disorders, from lead optimization through Phase I clinical testing. Eligible applicants are research organizations such as universities, colleges, government and tribal agencies, faith- or community-based organizations, and (for this announcement) foreign organizations; it is geared toward established research teams, not individuals or general nonprofits. Award amounts are not specified. Applicants should be prepared for a complex, multi-phase research undertaking with NIH-funded consultants and contract research organizations.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityNIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
Due Sep 7, 2027National Institutes of Health · Amount varies
This NIH (R13) program supports conferences and scientific meetings relevant to public health and the missions of participating NIH institutes. Eligible applicants are U.S. research and education organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Note that R13 conference support typically requires advance permission from the funding institute before applying. It is aimed at organizations hosting scientific conferences, not individuals. Award amounts are not specified.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreHEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
Due Jan 15, 2027National Institutes of Health · Up to $350K
This NIH HEAL Initiative R61/R33 funds early translational drug-discovery research toward non-addictive pain therapeutics, including assay development, screening, and initial characterization of candidate agents; no clinical trial is allowed. Eligible applicants include universities, research institutions, and tribal and community organizations, but foreign organizations are not eligible to apply. The maximum award is about $350,000. It requires drug-discovery research capacity.
ResearchersSchools & universitiesGovernment / tribalSmall award+1 moreNIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)
Due Dec 4, 2026National Institutes of Health · Amount varies
This NIH R50 award provides salary support for established Research Software Engineers who build and disseminate biomedical software, tools, and algorithms. Eligible applicants include universities and research institutions; foreign (non-U.S.) organizations are not eligible to apply. It is tied to an existing research environment and specialized staff, so it suits research institutions rather than general nonprofits or individuals applying on their own. No specific award amount is stated.
ResearchersSchools & universitiesBroad eligibilitySuccessor-in-Interest (Type 6 Parent Clinical Trial Optional)
Due Jul 17, 2027National Institutes of Health · Amount varies
This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityChange of Recipient Organization (Type 7 Parent Clinical Trial Optional)
Due Jul 12, 2027National Institutes of Health · Amount varies
This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilitySummer Research Education Experience Program (R25 Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH research education (R25) grant funds summer research experiences for high school or undergraduate students, or science teachers, tied to a participating institute's mission rather than general STEM. It is aimed at eligible institutions such as universities, nonprofits, and government agencies that would run the program; foreign organizations and foreign components are not allowed and clinical trials are not permitted. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityIndependent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH Independent Scientist Award (K02) provides salary support and protected time for newly independent investigators to intensify their research focus; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development leading to research independence; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityNIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development in biomedical, behavioral, or clinical research leading to independence, and this version requires an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.
ResearchersBroad eligibilityMentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree committed to patient-oriented research, providing protected research time under mentorship, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree who are committed to patient-oriented research, providing protected research time under mentorship. This version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilitySpecialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 (P50 Clinical Trial Required)
Due Sep 25, 2026National Institutes of Health · Amount varies
This NIH P50 SPORE grant funds translational cancer research centers focused on improving prevention, early detection, diagnosis, and treatment for a specific organ system or related group of cancers. Projects must have a clear path toward a translational human endpoint within the grant period, and it's aimed at eligible U.S. research institutions. The deadline is September 25, 2026.
ResearchersSchools & universitiesNarrow eligibility
Forecast opportunities under 93.121
7 opportunities have been announced by the issuing agency but are not accepting applications yet. Forecast notices usually carry no deadline and no application package until they post.
| Anticipated opportunity | Award range | Expected close |
|---|---|---|
| Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional) | Amount varies | Not announced |
| Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) | Amount varies | Not announced |
| NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed) | Amount varies | Not announced |
| Dental Primary Care Practice-Based Research Network: Coordinating Center | Amount varies | Not announced |
| Dental Primary Care Practice-Based Research Network: Administrative and Resource Center | Amount varies | Not announced |
| Dental Primary Care Practice-Based Research Network: Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement | Amount varies | Not announced |
| Small Business Translator: MedTech and Digital Health Technologies | Amount varies | Not announced |
Previously issued under this listing
Past rounds are the best guide to what the next one will look like — the scope, the award size, and the time of year it lands.
When 93.121 opportunities post
Across the 92 opportunities UseGrants has tracked under this listing, postings cluster in June, May, October, April. Federal program cycles repeat, so a listing that missed you this year is worth watching for the next round.
- June19 opportunities
- May15 opportunities
- October14 opportunities
- April10 opportunities
What is Assistance Listing 93.121?
93.121 is the federal Assistance Listing (formerly CFDA) number for Oral Diseases and Disorders Research, administered by National Institutes of Health. An Assistance Listing is the permanent catalogue entry for a funding program; individual notices of funding opportunity are issued under it, each with its own deadline and eligibility. UseGrants has tracked 92 such notices.
Are there open 93.121 grants right now?
Yes — 78 opportunities are currently accepting applications under 93.121, listed on this page with their deadlines and award amounts. 7 more are forecast: announced, but not yet open to applicants. Verify each on the issuing agency's official listing before you apply.
How much funding do 93.121 grants award?
The typical award ceiling for an opportunity under 93.121 is $350,000, ranging up to $4,000,000. Award floors and ceilings are set per opportunity — check the specific notice you intend to apply to.
Which agencies issue grants under 93.121?
National Institutes of Health has issued the opportunities UseGrants tracks under this listing. UseGrants is an independent aggregator compiling public Grants.gov records — always confirm current details on the agency's own listing.
Who applies to 93.121, and what it sits alongside
Related federal programs
Source: public Grants.gov opportunity records. Assistance Listing numbers and program titles are as published by the issuing agency. UseGrants is an independent aggregator, not a federal agency — always confirm the current deadline, eligibility and award amount on the official listing before you apply.