INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R21 funds exploratory, higher-risk Down syndrome research — feasibili…
- Deadline
- Jun 15, 2028
- Posted
- May 12, 2026
- Award amount
- Up to $200,000
- Focus areas
- Health
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We’ll email you before Jun 15, 2028 so you have time to apply.
In plain English
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R21 funds exploratory, higher-risk Down syndrome research — feasibility studies, novel methods, or new applications of existing techniques. Awards up to about $200,000.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
About this grant
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
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