Browse grants
Federal and state grant opportunities with plain-English eligibility summaries. We aggregate public records — always verify the details on the funder’s site before applying. Or browse the complete index →
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
Due Feb 8, 2028Food and Drug Administration · Up to $600K
This FDA award (up to $600,000) funds natural history studies that generate high-quality data to support medical product development for rare diseases with unmet needs. Eligibility is very broad, covering universities, nonprofits (with or without 501(c)(3) status), small and other for-profit businesses, tribal and local/state governments, and even foreign organizations and their non-U.S. components. No unusual disqualifiers are noted, and the deadline is not imminent.
NonprofitsSmall businessResearchersSchools & universities+3 moreNDEP STEM Open NFO
Due Feb 8, 2028Washington Headquarters Services · $100K–$10M
Open to industry, nonprofits, colleges and universities, and state or local educational agencies; foreign entities are not eligible. An ongoing 'open' announcement funding STEM education, outreach, and workforce-development programs for the Department of War's research enterprise, with specific topics released as amendments (often beginning with a white paper). Awards range widely, from about $100,000 to $10 million.
Small businessNonprofitsSchools & universitiesGovernment / tribal+1 moreTranslational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
Due May 7, 2028National Institutes of Health · Up to $1M
Open to U.S. universities, research institutions, nonprofits, foreign organizations, and certain government/tribal entities. This NIH R01 funds preclinical mouse-model testing of repurposed or investigational drugs — alone or with non-drug interventions — for Alzheimer's disease and related dementias. Awards up to about $1,000,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreCommunity-Partnered Nursing Research Centers (P20 Clinical Trial Optional)
Due May 7, 2028National Institutes of Health · Up to $500K
Open to U.S. schools and colleges of nursing and other research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH P20 funds new research centers that build nursing-led, community-partnered research infrastructure and pilot studies. Awards up to about $500,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreAnimal and Veterinary Innovation Centers (U18)
Due May 12, 2028Food and Drug Administration · Up to $1.3M
Open to public and private higher-education institutions, including HBCUs, tribal colleges, and other minority-serving institutions. This FDA U18 forms long-term academic partnerships to research avian influenza and emerging zoonotic threats, intentional genomic alterations in animals, and products for minor and veterinary species. Awards up to about $1,250,000.
Schools & universitiesResearchersGovernment / tribalLarge awardReissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
Due May 16, 2028Food and Drug Administration · Up to $900K
Open to nearly any organization — universities, nonprofits (with or without 501(c)(3)), for-profits and small businesses, state/local/tribal governments, and foreign organizations. This FDA R01 funds clinical trials of orphan products evaluating safety and efficacy to address unmet needs in rare diseases. Awards up to about $900,000; clinical trials are required.
ResearchersNonprofitsSmall businessGovernment / tribal+3 moreInstitutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)
Due May 26, 2028National Institutes of Health · Up to $2.1M
Open to U.S. research institutions and universities, nonprofits, and certain government/tribal organizations; foreign organizations cannot apply, and (as of May 2025) projects with foreign subawards are ineligible. This NIH U2C-TL1 funds institutional networks that recruit and train researchers in kidney, urologic, and hematologic disease research. Awards up to about $2,100,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreINCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
Due Jun 15, 2028National Institutes of Health · Up to $500K
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreBROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense
Due Jul 31, 2028Defense Health Agency Contracting Activity - DHACA · $750K–$50M
Open broadly to any type of entity — universities, nonprofits, businesses (including small businesses), and others. This Department of Defense / Defense Health Agency broad agency announcement funds extramural biomedical and human-performance research and development through FY28. Awards span a very wide range, from about $750,000 to $50 million.
ResearchersNonprofitsSmall businessSchools & universities+3 moreDefense Security Cooperation University - Research Grants
Due Aug 7, 2028Washington Headquarters Services · $2.5K–$800K
This Department of Defense program funds research on security cooperation and irregular warfare topics, open to individual researchers (with or without institutional affiliation), academic institutions, think tanks, and federally funded R&D centers; past awardees may reapply. Applicants can submit only one proposal at a time as principal investigator, and research products must be unclassified and made publicly accessible. Awards range from $2,500 to $800,000, and the deadline is not imminent.
NonprofitsResearchersIndividualsSchools & universities+3 moreDevelopment of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Due Aug 21, 2028National Institutes of Health · Up to $3M
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH UG3/UH3 funds discovery and development of interventions — medications and devices — to prevent and treat substance use disorders and overdose, including preclinical and clinical studies. Awards up to about $3,000,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreTransformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
Due Aug 21, 2028National Institutes of Health · Up to $500K
Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 funds development of non-invasive or minimally invasive technologies to image the human olfactory system at high resolution. Awards up to about $500,000; multidisciplinary teams are encouraged.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreVet-LIRN Capacity-Building Project and Equipment Grants (U18)
Due Sep 4, 2028Food and Drug Administration · $225K–$2.5M
This FDA grant (U18, $225,000 to $2,500,000) funds veterinary diagnostic laboratories in the Vet-LIRN network to build capacity for animal food safety and antimicrobial resistance testing, including equipment and method development. Eligibility is broad, covering nonprofits (with or without 501(c)(3) status), small businesses, for-profit organizations, universities, tribal governments, and state/local governments. No unusual disqualifiers are noted, and the deadline is not imminent.
NonprofitsSmall businessGovernment / tribalSchools & universities+2 moreLimited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)
Due Sep 25, 2028National Institutes of Health · Up to $1.8M
This NIH/NIEHS P42 grant funds Superfund Research Program Centers that combine biomedical and environmental science and engineering to study hazardous substances. By law, eligibility is limited to accredited institutions of higher education, though they may subcontract with other organizations and governments. Awards are large (up to roughly $1.75M), and foreign organizations and foreign components of U.S. organizations are not eligible to apply.
Schools & universitiesResearchersLarge awardNarrow eligibilityDrinking Water Fluoridation RFA
UnofficialDue Sep 28, 2028Department of Health · Up to $2.5M
The New York State Department of Health's Drinking Water Fluoridation RFA funds eligible NYS municipalities to plan (Component A) or implement/maintain (Component B) community water fluoridation systems, with awards up to $2,500,000, on a rolling submission basis. While listed eligibility includes for-profit, governmental, and not-for-profit entities, the program description specifically targets NYS municipalities, so applicants should confirm municipal eligibility before applying. The deadline is September 28, 2028.
NonprofitsGovernment / tribalLarge awardNarrow eligibilityOccupational Safety and Health Education and Research Centers (T42)
Due Oct 26, 2028Centers for Disease Control and Prevention - ERA · $4.5M–$9M
This CDC/NIOSH program funds academic institutions to run Education and Research Centers providing interdisciplinary training and research in occupational safety and health. Awards are large (roughly $4.5M to $9M). Eligibility is narrow: only one application per institution is allowed, and current holders of a NIOSH T03 training grant cannot receive an award or sub-award under this opportunity.
Schools & universitiesResearchersLarge awardNarrow eligibilityOccupational Safety and Health Training Project Grants (T03)
Due Oct 26, 2028Centers for Disease Control and Prevention - ERA · $50K–$550K
This CDC/NIOSH T03 program funds Training Project Grants for occupational safety and health education, mostly at academic institutions providing undergraduate, graduate, and post-graduate training, plus a limited number of non-academic awards for specialized audiences. Awards range from roughly $50,000 up to about $550,000. Foreign organizations are not eligible to apply.
Schools & universitiesResearchersLarge awardThe Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Due Nov 22, 2028National Institutes of Health · Up to $500K
This NIH/NCI U01 cooperative agreement funds research projects within the Metastasis Research Network that use systems-level approaches to study cancer metastasis as a whole-body problem. Both U.S. and foreign organizations may apply, but applications including funded foreign subawards/subcontracts will be deemed noncompliant. The award ceiling is up to about $500,000.
ResearchersSchools & universitiesLarge awardBroad eligibilityFOUNDATIONS OF TRUSTED SYSTEMS
Due Dec 5, 2028Air Force -- Research Lab · Up to $99.9M
This is an Air Force Research Lab research-and-development opportunity (Foundations of Trusted Systems) for organizations working in defense-related science and technology. The total ceiling across the program is very large (up to roughly $99.9M), so awards typically go to established research institutions, universities, and contractors rather than small applicants. Full eligibility and requirements are only in the linked SAM.gov notice, so review that posting before applying.
ResearchersSchools & universitiesLarge awardNarrow eligibilityUpdated National Dislocated Worker Grant Program Guidance and Application Information
Due Dec 31, 2028Employment and Training Administration · $150K–$10M
This U.S. Department of Labor program provides National Dislocated Worker Grants to help communities respond to layoffs and disasters that displace workers. Eligibility is restricted to government and workforce entities such as state workforce agencies, local Workforce Development Boards, outlying areas, and Indian tribal governments, depending on the grant type; individual nonprofits and businesses are not direct applicants. Awards are large, ranging from about $150,000 up to roughly $10M.
Government / tribalLarge awardNarrow eligibility