Grants for Nonprofits

National Institutes of Health · Up to $50K

The NIH parent Small Research Grant (R03, clinical trial not allowed) supports small, short-term projects such as pilot and feasibility studies, secondary data analysis, and methodology development. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget suits research institutions pursuing limited-scope projects to generate preliminary data.

National Institutes of Health · Up to $500K

An NIH/NCI research project grant (R01) funding projects that integrate medical imaging with fluid-based (liquid biopsy) tumor monitoring during cancer therapy. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. The award is capped at about $500,000. This is an oncology research mechanism aimed at research institutions, not individuals or general nonprofits.

National Institutes of Health · Up to $200K

An NIH (R21) exploratory grant funding invasive neural recording and stimulation studies in humans to understand neural circuitry underlying mental health disorders. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $200,000. Technology and therapy development are out of scope, so this suits research institutions conducting specific neuroscience studies.

National Institutes of Health · Up to $150K

An NIH Small Research Grant (I/START, R03) designed to help investigators enter brain-imaging research with small proof-of-concept studies relevant to substance use and addiction. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $150,000. It supports newly independent and established investigators through their institutions, not individuals applying directly.

National Institutes of Health · Amount varies

An NIH/NCI research project grant (R01, clinical trial not allowed) funding basic, mechanistic research into the biological and genetic causes of cancer health disparities. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science oncology mechanism aimed at research institutions building expertise in cancer disparities.

National Institutes of Health · Up to $499K

An NIH/NCI research project grant (R01) funding academic-industrial partnerships to translate scientific and engineering advances into tools for disease risk assessment, detection, diagnosis, and treatment. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $499,000. The partnership focus suits research institutions collaborating with industry rather than individuals.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trials optional) supporting multi-level intervention research to reduce disparities in liver diseases and liver cancer among U.S. populations experiencing health disparities. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components of U.S. organizations are not eligible, though foreign components within the project are allowed. No specific award amount is stated. This suits research institutions focused on health-disparities intervention research.

National Institutes of Health · Up to $150K

An NIH/NEI planning grant (R34, clinical trial not allowed) supporting development of study protocols and manuals of procedures for future clinical vision research, including trials and epidemiologic studies. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $150,000. Funds cannot be used to generate intervention-effect data, so this is a planning mechanism for research institutions.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trials not allowed) supporting innovative, non-trial mental health services research aligned with NIMH strategic priorities. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This suits research institutions conducting services research rather than intervention trials.

National Institutes of Health · Up to $225K

An NIH/NIMH pilot research grant (R34, clinical trial not allowed) supporting mental health services research that is not an immediate precursor to a service-intervention trial but aligns with NIMH priorities. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $225,000. This suits research institutions conducting non-trial pilot services research.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial optional) funding invasive neural recording and stimulation studies in humans to understand neural circuitry underlying mental health disorders. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. Technology and therapy development are out of scope, so this suits research institutions conducting specific neuroscience studies.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial optional) funding multi-level health-care research to improve care for older adults from populations that experience health disparities. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. No specific award amount is stated. This suits research institutions focused on aging and health-disparities care research.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding pilot effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions running pilot effectiveness studies.

National Institutes of Health · Up to $200K

An NIH/NCMRR Early Career Research Award (R03, clinical trial optional) supporting basic and clinical rehabilitation research from scientists establishing independent careers, intended to generate preliminary data for a later R01. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $200,000. This is an early-career research mechanism administered through a sponsoring institution.

National Institutes of Health · Amount varies

Open to a broad range of research organizations including universities, minority-serving institutions, tribal governments, faith- and community-based organizations, and foreign organizations under this NIH R03 small-grant mechanism. Funds research that develops and tests strategies to spread, scale up, sustain, or de-implement evidence-based health interventions, practices, and policies. Work must fall within the mission of a participating NIH Institute or Center; no clinical trial is allowed and no specific award ceiling is stated.

National Institutes of Health · Amount varies

Open to a wide range of research organizations including universities, minority-serving institutions, tribal governments, faith- and community-based organizations, and foreign organizations under this NIH R21 exploratory mechanism. Funds development of next-generation brain stimulation (neuromodulation) devices to treat mental health disorders, either creating novel devices or substantially improving FDA-approved ones; incremental software updates are out of scope. Applications should come from multidisciplinary teams spanning neuroscience, engineering, clinical, and regulatory expertise, and no clinical trial is allowed.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions across the lifespan. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and faith- or community-based organizations. No specific award ceiling is stated. This requires conducting a clinical trial, so it suits research institutions with that capacity rather than individuals or general nonprofits.

National Institutes of Health · Up to $50K

An NIH/NICHD Small Research Grant (R03, clinical trial required) supporting small clinical-trial projects within the NICHD mission. Eligible applicants include a broad range of domestic and foreign institutions such as universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget and clinical-trial requirement make this best suited to research institutions running limited-scope pilot trials.

National Institutes of Health · Amount varies

An NIH/NIMH planning grant (R34, clinical trial required) funding research on family-navigation emergency-department diversion models for non-urgent mental health concerns. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. No specific award amount is stated. This requires a clinical trial and suits research institutions in mental health services research.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding research on family-navigation emergency-department diversion models for non-urgent mental health concerns. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions in mental health services research.