Allergy and Infectious Diseases Research Grants (Assistance Listing 93.855)

National Institutes of Health · Amount varies

This NIH/NIAID (U01) cooperative agreement funds the implementation of investigator-initiated, milestone-driven clinical trials that need enhanced oversight, optionally including mechanistic studies, for up to 5 (or extended 6-7) years. A clinical trial is required and only one trial may be proposed per application, so it suits research institutions ready to run a defined trial in infectious disease or immunology. Eligibility is comparatively open for NIH: foreign organizations and foreign components of U.S. organizations are both eligible to apply, and foreign components are allowed.

National Institutes of Health · Amount varies

This NIH Predoctoral-to-Postdoctoral Transition Award (F99/K00) supports promising graduate students as they finish doctoral research and move into mentored postdoctoral career development, in NIH mission-relevant fields. It is a mentored training award administered through institutions; candidates may not lead an independent clinical trial but may participate in a sponsor-led one. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH SBIR Phase IIB award is restricted to U.S. small business concerns that have previously received an NIH SBIR or STTR Phase II award; it bridges the gap between Phase II and commercialization for later-stage R&D. Only one such award is allowed per project, and applications must be submitted within the first six due dates after the Phase II budget period ends, so it is narrow and limited to existing grantees. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH SBIR/STTR Commercialization Readiness Pilot (CRP) is restricted to U.S. small business concerns (as defined by the SBA) and helps move NIH-funded SBIR/STTR projects from late-stage development toward commercialization. It supports later-stage R&D and technical assistance such as replication studies, IND/IDE-enabling work, clinical studies, manufacturing scale-up, and regulatory support, and a significant portion may be subcontracted. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH career development award (K32) supports up to three years of mentored research and career development for early-stage postdoctoral scholars, with applications submitted around the start of the postdoctoral position. It is an institutional/mentored mechanism aimed at developing future independent investigators, so it suits universities and research institutions. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Up to $500K

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.

National Institutes of Health · Up to $200K

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R21 funds exploratory, higher-risk Down syndrome research — feasibility studies, novel methods, or new applications of existing techniques. Awards up to about $200,000.

National Institutes of Health · Amount varies

This NIH/NIAID Program Project (P01) opportunity funds multi-component research programs in infectious disease and immunology, including HIV, immune dysfunction, allergy, autoimmunity, and vaccine/therapeutic/diagnostic development. Each application must include at least two related research projects plus an administrative core, so it is geared toward research institutions with established teams. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed. Clinical trials are not permitted under this NOFO.

National Institutes of Health · Amount varies

This NIH/NIAID Resource-Related Research Project (R24) opportunity funds the creation or support of shared scientific resources that benefit high-priority research in infectious disease and immunology. NIAID expects to use it infrequently, only when other funding mechanisms are not appropriate, so it is a narrow opportunity for research institutions. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed, and clinical trials are not permitted.

National Institutes of Health · Amount varies

The NIH Science Education Partnership Award (SEPA, R25) funds educational projects that increase understanding of biomedical research among pre-college (pre-K through grade 12) students and encourage interest in STEM careers. It suits universities, research institutions, and education-focused organizations that can run science education programs. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Up to $300K

This NIH R01 grant funds basic research into how toxic chemicals of concern injure the skin, supporting the development of medical countermeasures for chemical disasters and emergencies. The award ceiling is up to about $300,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.

National Institutes of Health · Amount varies

This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.

National Institutes of Health · Amount varies

An NIH (R38) award supporting in-depth research experiences for resident clinicians early in their careers to build a pipeline of clinician-investigators. Eligible applicants are domestic institutions and organizations such as universities, tribal governments, and faith- or community-based organizations; foreign organizations and foreign components are not eligible. No award amount is stated. This is a structured research-training mechanism aimed at academic and clinical institutions rather than individuals applying directly.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government and tribal organizations; foreign organizations are not eligible. This NIH R21 funds exploratory, early-stage projects developing methods or agents to target 'undruggable' molecules in serious diseases. Award size isn't specified and follows standard NIH R21 limits; best suited to researchers pursuing high-risk, innovative therapeutics.

National Institutes of Health · Up to $100K

This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.

National Institutes of Health · Up to $125K

This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students in combined MD/PhD or similar dual-doctoral degree programs at institutions that already have an NIH-funded dual-degree training program, preparing them for physician-scientist careers. It is limited to individual student applicants; foreign organizations and their non-U.S. components are not eligible, and applicants may not lead an independent clinical trial. No award amount is listed, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual predoctoral students conducting dissertation research in health-related fields under a faculty sponsor, with the goal of developing them into independent researchers. It is limited to individual applicants (not organizations); foreign organizations are named as an other-eligible category, and applicants may not lead an independent clinical trial. No specific award amount is listed, and the deadline is several years out.

National Institutes of Health · Amount varies

This NIH R01 funds larger-scale research testing and disseminating interventions to improve health in Native American populations, following the same research focus as its companion R34 announcement. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with foreign entities restricted. No award amount is specified.

National Institutes of Health · Amount varies

This NIH R01 grant funds research applications studying the ethical, legal, and social implications of human genetics and genomics, using empirical, conceptual, legal, or normative methods. Applications must include a Plan for Enhancing Diverse Perspectives (PEDP); those without one won't be reviewed. It's aimed at eligible U.S. and territorial research institutions, and the deadline is November 18, 2026.

National Institutes of Health · Up to $50K

This NIH grant (up to $50,000) funds small research projects studying the ethical, legal, and social implications (ELSI) of human genetics and genomics, including single-investigator studies, preliminary data collection, and secondary data analysis. It's aimed at eligible U.S. and territorial research institutions. The deadline is November 16, 2026.

National Institutes of Health · Amount varies

This NIH R21 grant funds exploratory and developmental research into the ethical, legal, and social implications of human genetics and genomics, particularly studies examining new or emerging genomic technologies. It's open to eligible U.S. and territorial research institutions using empirical, conceptual, legal, or normative methods. The deadline is November 18, 2026.

National Institutes of Health · Up to $50K

The NIH parent Small Research Grant (R03, clinical trial not allowed) supports small, short-term projects such as pilot and feasibility studies, secondary data analysis, and methodology development. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget suits research institutions pursuing limited-scope projects to generate preliminary data.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial required) supports early-stage research projects with at least one clinical trial, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Up to $650K

This NIH limited-competition award (UG3/UH3) funds collaborative innovation projects within the CTSA Program consortium to accelerate translational research. Eligibility is restricted per the funding notice, and foreign organizations and their U.S. components are not eligible, so this is aimed at institutions already in or aligned with the CTSA consortium rather than the general public. Awards run up to roughly $650,000. Review the notice's eligibility section closely, as access is limited.

National Institutes of Health · Up to $375K

The REAP program funds small-scale research at health professional and graduate schools that haven't been major recipients of NIH support, while giving students hands-on research experience. Eligibility is limited to institutions awarding NIH-relevant degrees that received under $6 million per year in NIH support in 4 of the last 7 years — a specific financial threshold worth checking before applying. Awards go up to $375,000.

National Institutes of Health · Up to $150K

An NIH/NIAID Career Transition Award (K22) to help postdoctoral fellows move into assistant-professor or equivalent positions and launch independent biomedical research careers. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. The award is capped at about $150,000. This is a career-development mechanism oriented to early-career researchers working through a sponsoring institution.

National Institutes of Health · Up to $375K

An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.

National Institutes of Health · Amount varies

This NHLBI Catalyze (R61/R33) phased opportunity funds target identification and validation plus preliminary product or lead-series identification for small molecules, biologics, and combination products treating heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.

National Institutes of Health · Amount varies

This NHLBI Catalyze (R33) opportunity funds early-stage translational work to identify and characterize therapeutic candidates and combination products (small molecules and biologics) for heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.

National Institutes of Health · Up to $300K

This NIH (R01) opportunity funds basic research into the harmful effects of acute exposure to ultra-potent synthetic opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations, including delayed effects. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $300,000.

National Institutes of Health · Amount varies

This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.

National Institutes of Health · Up to $300K

This NIH (CounterACT) R01 funds basic research on how chemical warfare agents, toxic industrial chemicals, and pesticides affect the nervous system, aimed at understanding toxicity mechanisms and identifying therapeutic targets. Eligible applicants include higher-education institutions, nonprofits, tribal governments, faith- or community-based organizations, and federal agencies; clinical trials are not allowed. Foreign (non-U.S.) organizations and the foreign components of U.S. organizations are not eligible to apply. The award appears to be roughly $300,000 in stated funding.

National Institutes of Health · Amount varies

This NIH R21 funds exploratory research on dissemination and implementation strategies for evidence-based health interventions, including studies on de-implementing low-value practices. Eligible applicants include universities and similar research institutions across NIH's mission areas. No award amount is specified.

National Institutes of Health · Amount varies

This NIH R01 funds research identifying and testing strategies to help evidence-based health interventions get adopted, scaled, and sustained — or, conversely, to phase out ineffective practices. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations across NIH's mission areas. No award amount is specified.

National Institutes of Health · Up to $100K

This NIH (R03) opportunity funds pilot projects generating preliminary data on a defined list of understudied proteins associated with rare diseases. It is intended for research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $100,000.

National Institutes of Health · Amount varies

A limited-competition NIH planning grant (R34, clinical trial not allowed) supporting fundamental research on skin injuries caused by chemical threats and potential shared therapeutic targets. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components of U.S. organizations are not eligible, though foreign components within the project are allowed. No specific award amount is stated. As a limited competition, eligibility may be further restricted beyond the listed categories, so review the NOFO closely.

National Institutes of Health · Amount varies

This NIH (R13) program supports conferences and scientific meetings relevant to public health and the missions of participating NIH institutes. Eligible applicants are U.S. research and education organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Note that R13 conference support typically requires advance permission from the funding institute before applying. It is aimed at organizations hosting scientific conferences, not individuals. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH midcareer award (K24) provides protected time for mid-career clinician-scientists to conduct patient-oriented research and mentor junior clinical researchers; this version does not allow leading an independent clinical trial. It is intended for individual health-professional investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH midcareer award (K24) provides protected time for mid-career clinician-scientists to conduct patient-oriented research and mentor junior clinical researchers, and this version requires an independent clinical trial. It is intended for individual health-professional investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development leading to research independence; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree who are committed to patient-oriented research, providing protected research time under mentorship. This version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.